(1α, 5α, 6α)-6-N-(3-azabicyclo [3.1.0] hexyl-3-(4-methyl-3-pentenyl))-2-cyclopentyl-2-hydroxy-2-phenyl acetamide

Base Information

Chemical Name:(1α, 5α, 6α)-6-N-(3-azabicyclo [3.1.0] hexyl-3-(4-methyl-3-pentenyl))-2-cyclopentyl-2-hydroxy-2-phenyl acetamide
CAS No.:712356-15-5
Molecular Formula:C₂₄H₃₄N₂O₂
Molecular Weight:382.546
Hs Code.:

Synonyms:(1α, 5α, 6α)-6-N-(3-azabicyclo [3.1.0] hexyl-3-(4-methyl-3-pentenyl))-2-cyclopentyl-2-hydroxy-2-phenyl acetamide

Suppliers and Price of (1α, 5α, 6α)-6-N-(3-azabicyclo [3.1.0] hexyl-3-(4-methyl-3-pentenyl))-2-cyclopentyl-2-hydroxy-2-phenyl acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1α, 5α, 6α)-6-N-(3-azabicyclo [3.1.0] hexyl-3-(4-methyl-3-pentenyl))-2-cyclopentyl-2-hydroxy-2-phenyl acetamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1α, 5α, 6α)-6-N-(3-azabicyclo [3.1.0] hexyl-3-(4-methyl-3-pentenyl))-2-cyclopentyl-2-hydroxy-2-phenyl acetamide

There total 7 articles about (1α, 5α, 6α)-6-N-(3-azabicyclo [3.1.0] hexyl-3-(4-methyl-3-pentenyl))-2-cyclopentyl-2-hydroxy-2-phenyl acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1603-79-8
phenylglyoxylic acid ethyl ester

: 712356-15-5
(1α, 5α, 6α)-6-N-(3-azabicyclo [3.1.0] hexyl-3-(4-methyl-3-pentenyl))-2-cyclopentyl-2-hydroxy-2-phenyl acetamide

Guidance literature:: Multi-step reaction with 5 steps

1: tetrahydrofuran / 0 - 20 °C

2: KOH / methanol / 20 °C

3: 1-hydroxybenzotriazole; N-methylmorpholine; N-ethyl-N'-(3-dimethylaminopropyl)-N'-ethylcarbodiimide*HCl / dimethylformamide

4: H₂ / Pd/C / methanol / 3 h / 20 °C / 2327.23 Torr

5: potassium carbonate; potassium iodide / acetonitrile / 8 h / Heating

With 4-methyl-morpholine; potassium hydroxide; hydrogen; potassium carbonate; benzotriazol-1-ol; potassium iodide; palladium on activated charcoal; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.bmcl.2007.06.081

Reference yield:

: 712356-14-4
(1α, 5α ,6α)-6-N-(3-azabicyclo[3.1.0] hexyl-3-benzyl)-2-cyclopentyl-2-hydroxy-2-phenyl acetamide

: 712356-15-5
(1α, 5α, 6α)-6-N-(3-azabicyclo [3.1.0] hexyl-3-(4-methyl-3-pentenyl))-2-cyclopentyl-2-hydroxy-2-phenyl acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd/C / methanol / 3 h / 20 °C / 2327.23 Torr

2: potassium carbonate; potassium iodide / acetonitrile / 8 h / Heating

With hydrogen; potassium carbonate; potassium iodide; palladium on activated charcoal; In methanol; acetonitrile;
DOI:10.1016/j.bmcl.2007.06.081

Reference yield:

: 16098-80-9
2-cyclopentyl-2-hydroxy-2-phenylacetic acid ethyl ester

: 712356-15-5
(1α, 5α, 6α)-6-N-(3-azabicyclo [3.1.0] hexyl-3-(4-methyl-3-pentenyl))-2-cyclopentyl-2-hydroxy-2-phenyl acetamide

Guidance literature:: Multi-step reaction with 4 steps

1: KOH / methanol / 20 °C

2: 1-hydroxybenzotriazole; N-methylmorpholine; N-ethyl-N'-(3-dimethylaminopropyl)-N'-ethylcarbodiimide*HCl / dimethylformamide

3: H₂ / Pd/C / methanol / 3 h / 20 °C / 2327.23 Torr

4: potassium carbonate; potassium iodide / acetonitrile / 8 h / Heating

With 4-methyl-morpholine; potassium hydroxide; hydrogen; potassium carbonate; benzotriazol-1-ol; potassium iodide; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.bmcl.2007.06.081