[4-hydroxy-5-methoxy-3-(3',7'-dimethyl-2',6'-octadienyl)benzyloxy]-tert-butyldimethylsilane

Base Information

Chemical Name:[4-hydroxy-5-methoxy-3-(3',7'-dimethyl-2',6'-octadienyl)benzyloxy]-tert-butyldimethylsilane
CAS No.:474970-87-1
Molecular Formula:C₂₄H₄₀O₃Si
Molecular Weight:404.665
Hs Code.:

Synonyms:[4-hydroxy-5-methoxy-3-(3',7'-dimethyl-2',6'-octadienyl)benzyloxy]-tert-butyldimethylsilane

Suppliers and Price of [4-hydroxy-5-methoxy-3-(3',7'-dimethyl-2',6'-octadienyl)benzyloxy]-tert-butyldimethylsilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [4-hydroxy-5-methoxy-3-(3',7'-dimethyl-2',6'-octadienyl)benzyloxy]-tert-butyldimethylsilane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [4-hydroxy-5-methoxy-3-(3',7'-dimethyl-2',6'-octadienyl)benzyloxy]-tert-butyldimethylsilane

There total 4 articles about [4-hydroxy-5-methoxy-3-(3',7'-dimethyl-2',6'-octadienyl)benzyloxy]-tert-butyldimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: tert-butyl-[3-(3,7-dimethyl-octa-2,6-dienyl)-4-(2-ethoxy-ethoxy)-5-methoxy-benzyloxy]-dimethyl-silane

: 474970-87-1
[4-hydroxy-5-methoxy-3-(3',7'-dimethyl-2',6'-octadienyl)benzyloxy]-tert-butyldimethylsilane

Guidance literature:: With acetyl chloride; In methanol; at 0 ℃; for 0.333333h;
DOI:10.1021/ol0266368

Reference yield:

: 2316-61-2
5-bromo-4-hydroxy-3-methoxybenzyl alcohol

: 474970-87-1
[4-hydroxy-5-methoxy-3-(3',7'-dimethyl-2',6'-octadienyl)benzyloxy]-tert-butyldimethylsilane

Guidance literature:: Multi-step reaction with 5 steps

1.1: 91 percent / imidazole / CH₂Cl₂ / 18 h / 20 °C

2.1: 98 percent / TBAF / tetrahydrofuran / 1 h / 0 °C

3.1: 81 percent / PPTS / CH₂Cl₂ / 40 h / 20 °C

4.1: n-BuLi / tetrahydrofuran; hexane / 0.58 h / -78 °C

4.2: tetrahydrofuran; hexane / 20 h / 20 °C

5.1: 6.13 g / acetyl chloride / methanol / 0.33 h / 0 °C

With 1H-imidazole; n-butyllithium; tetrabutyl ammonium fluoride; pyridinium p-toluenesulfonate; acetyl chloride; In tetrahydrofuran; methanol; hexane; dichloromethane;
DOI:10.1021/ol0266368

Reference yield:

: 474970-83-7
(5-bromo-4-hydroxy-3-methoxybenzyloxy)-tert-butyldimethylsilane

: 474970-87-1
[4-hydroxy-5-methoxy-3-(3',7'-dimethyl-2',6'-octadienyl)benzyloxy]-tert-butyldimethylsilane

Guidance literature:: Multi-step reaction with 3 steps

1.1: 81 percent / PPTS / CH₂Cl₂ / 40 h / 20 °C

2.1: n-BuLi / tetrahydrofuran; hexane / 0.58 h / -78 °C

2.2: tetrahydrofuran; hexane / 20 h / 20 °C

3.1: 6.13 g / acetyl chloride / methanol / 0.33 h / 0 °C

With n-butyllithium; pyridinium p-toluenesulfonate; acetyl chloride; In tetrahydrofuran; methanol; hexane; dichloromethane;
DOI:10.1021/ol0266368