methyl 3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside

Base Information

Chemical Name:methyl 3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside
CAS No.:1381871-28-8
Molecular Formula:C₃₁H₃₈O₉S
Molecular Weight:586.703
Hs Code.:

Synonyms:methyl 3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside

Suppliers and Price of methyl 3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside

There total 3 articles about methyl 3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1381871-26-6
methyl 3,4,7-tri-O-benzyl-5-O-((2-naphthyl)methyl)-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside

: 1381871-28-8
methyl 3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside

Guidance literature:: With water; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; at 20 ℃; for 0.333333h; chemoselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2012.04.067

Reference yield:

: 1381871-18-6
ethyl 3,4,7-tri-O-benzyl-5-O-((2-naphthyl)methyl)-1-deoxy-1-ethoxysulfonyl-2-thio-α-D-gluco-hept-2-ulopyranoside

: 1381871-28-8
methyl 3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: N-iodo-succinimide; trifluorormethanesulfonic acid / tetrahydrofuran; dichloromethane / 0.33 h / -20 °C / Inert atmosphere; Molecular sieve

2: water; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 0.33 h / 20 °C / Inert atmosphere

With N-iodo-succinimide; trifluorormethanesulfonic acid; water; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tet.2012.04.067

Reference yield:

: 2,3,6-tri-O-benzyl-4-O-((2-naphthyl)methyl)-α,β-D-glucopyranose

: 1381871-28-8
methyl 3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside

Guidance literature:: Multi-step reaction with 5 steps

1.1: Dess-Martin periodane / dichloromethane / 0.5 h / 20 °C / Inert atmosphere

2.1: n-butyllithium; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 0.25 h / -60 °C / Inert atmosphere

2.2: 3 h / -78 - -60 °C / Inert atmosphere

2.3: Inert atmosphere

3.1: boron trifluoride diethyl etherate / dichloromethane / 0 °C / Inert atmosphere

4.1: N-iodo-succinimide; trifluorormethanesulfonic acid / tetrahydrofuran; dichloromethane / 0.33 h / -20 °C / Inert atmosphere; Molecular sieve

5.1: water; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 0.33 h / 20 °C / Inert atmosphere

With N-iodo-succinimide; n-butyllithium; trifluorormethanesulfonic acid; boron trifluoride diethyl etherate; water; Dess-Martin periodane; N-ethyl-N,N-diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; dichloromethane; 1.1: Dess-Martin oxidation;
DOI:10.1016/j.tet.2012.04.067