C₃₅H₃₈O₄

Base Information

• Chemical Name: C₃₅H₃₈O₄
• CAS No.: 351885-63-7
• Molecular Formula: C₃₅H₃₈O₄
• Molecular Weight: 522.684
• Mol file: 351885-63-7.mol

Synonyms:C₃₅H₃₈O₄

Chemical Property of C₃₅H₃₈O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₅H₃₈O₄

There total 6 articles about C₃₅H₃₈O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

norborn-2-ene (498-66-8) → C35H38O4 (351885-63-7)

Guidance literature:

Multi-step reaction with 6 steps

1.1: aq. K₃Fe(CN)6; K₂OsO₄; quinuclidine / K₂CO₃ / 2-methyl-propan-2-ol

2.1: aq. NaIO₄ / tetrahydrofuran / 0 - 20 °C

3.1: t-BuOK / tetrahydrofuran / 2 h / 0 - 20 °C

3.2: 90 percent / tetrahydrofuran / -78 - 4 °C

4.1: 87 percent / (CH₃)3Al; AlCl₃ / CH₂Cl₂ / 4 °C

5.1: LiAlH₄ / tetrahydrofuran / 20 °C

6.1: Et₃N / CH₂Cl₂ / 20 °C

With Quinuclidine; potassium osmate(VI); sodium periodate; lithium aluminium tetrahydride; aluminium trichloride; potassium tert-butylate; trimethylaluminum; triethylamine; potassium hexacyanoferrate(III); potassium carbonate; In tetrahydrofuran; dichloromethane; tert-butyl alcohol; 1.1: Sharpless dihydroxylation / 3.2: Horner-Wadsworth-Emmons reaction / 4.1: Diels-Alder cycloaddition;

DOI:10.1021/ja003712y

Reference yield:

benzoyl chloride (98-88-4) + {(1R,2S,3S,4S)-3-[(1S,3R)-3-((1R,2R,3R,4S)-3-Hydroxymethyl-bicyclo[2.2.1]hept-5-en-2-yl)-cyclopentyl]-bicyclo[2.2.1]hept-5-en-2-yl}-methanol (522617-86-3) → C35H38O4 (351885-63-7)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1021/ja003712y

Reference yield:

2,3-dihydroxybicyclo[2.2.1]hept-5-an (14440-78-9) → C35H38O4 (351885-63-7)

Guidance literature:

Multi-step reaction with 5 steps

1.1: aq. NaIO₄ / tetrahydrofuran / 0 - 20 °C

2.1: t-BuOK / tetrahydrofuran / 2 h / 0 - 20 °C

2.2: 90 percent / tetrahydrofuran / -78 - 4 °C

3.1: 87 percent / (CH₃)3Al; AlCl₃ / CH₂Cl₂ / 4 °C

4.1: LiAlH₄ / tetrahydrofuran / 20 °C

5.1: Et₃N / CH₂Cl₂ / 20 °C

With sodium periodate; lithium aluminium tetrahydride; aluminium trichloride; potassium tert-butylate; trimethylaluminum; triethylamine; In tetrahydrofuran; dichloromethane; 2.2: Horner-Wadsworth-Emmons reaction / 3.1: Diels-Alder cycloaddition;

DOI:10.1021/ja003712y

upstream raw materials:

benzoyl chloride

{(1R,2S,3S,4S)-3-[(1S,3R)-3-((1R,2R,3R,4S)-3-Hydroxymethyl-bicyclo[2.2.1]hept-5-en-2-yl)-cyclopentyl]-bicyclo[2.2.1]hept-5-en-2-yl}-methanol

norborn-2-ene

2,3-dihydroxybicyclo[2.2.1]hept-5-an

Downstream raw materials:

C₃₅H₄₆O₈