Colforsin daropate

Base Information

Chemical Name:Colforsin daropate
CAS No.:113462-26-3
Molecular Formula:C₂₇H₄₃NO₈
Molecular Weight:509.64
Hs Code.:
UNII:1196KQZ976
DSSTox Substance ID:DTXSID20150415
Nikkaji Number:J463.673B
Wikipedia:Colforsin_daropate
Wikidata:Q76100332
Pharos Ligand ID:GNSDP7C1WW9P
ChEMBL ID:CHEMBL4303178
Mol file:113462-26-3.mol

Synonyms:colforsin daropate;colforsin daropate hydrochloride

Suppliers and Price of Colforsin daropate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Colforsin daropate

Chemical Property:

PSA：122.60000
LogP:2.02250
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:8
Exact Mass:509.29886733
Heavy Atom Count:36
Complexity:933

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)OC(=O)CCN(C)C
Isomeric SMILES:CC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)OC(=O)CCN(C)C

Technology Process of Colforsin daropate

There total 6 articles about Colforsin daropate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: 75-36-5
acetyl chloride

: 113462-31-0
6β-(3-dimethylaminopropionyloxy)-1α,7β,9α-trihydroxy-8,13-epoxy-labd-14-en-11-one

: 113462-26-3
NKH477

Guidance literature:: In dichloromethane; for 7h;
DOI:10.1248/cpb.44.2274

Reference yield:

: 105535-46-4
1α-<(tert-butyldimethylsilyl)oxy>-8,13-epoxy-6β,7β,9α-trihydroxylabd-14-en-11-one

: 113462-26-3
NKH477

Guidance literature:: Multi-step reaction with 5 steps

1: pyridine / CH₂Cl₂ / Ambient temperature

2: CH₂Cl₂ / 2 h / Ambient temperature

3: trifluoroacetic acid / methanol / 43 h / Ambient temperature

4: 87 percent / 1N NaOH / acetonitrile; H₂O / 0.42 h / Ambient temperature

5: 32 percent / CH₂Cl₂ / 7 h

With pyridine; sodium hydroxide; trifluoroacetic acid; In methanol; dichloromethane; water; acetonitrile;
DOI:10.1248/cpb.44.2274

Reference yield:

: 113462-16-1
3-Dimethylamino-propionic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyl-dodecahydro-benzo[f]chromen-5-yl ester

: 113462-26-3
NKH477

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / 1N NaOH / acetonitrile; H₂O / 0.42 h / Ambient temperature

2: 32 percent / CH₂Cl₂ / 7 h

With sodium hydroxide; In dichloromethane; water; acetonitrile;
DOI:10.1248/cpb.44.2274