1,1-diphenyl-O-acetylvinylcarbinol

Base Information

• Chemical Name: 1,1-diphenyl-O-acetylvinylcarbinol
• CAS No.: 3848-50-8
• Molecular Formula: C₁₇H₁₆O₂
• Molecular Weight: 252.313
• Mol file: 3848-50-8.mol

Synonyms:1,1-diphenyl-O-acetylvinylcarbinol

Chemical Property of 1,1-diphenyl-O-acetylvinylcarbinol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1-diphenyl-O-acetylvinylcarbinol

There total 5 articles about 1,1-diphenyl-O-acetylvinylcarbinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

1,1-diphenylprop-2-en-1-ol (3923-51-1) + acetic anhydride (108-24-7) → 1,1-diphenyl-O-acetylvinylcarbinol (3848-50-8)

Guidance literature:

With potassium hydroxide; for 3h; Heating;

DOI:10.1007/BF00758309

Reference yield:

benzophenone (119-61-9) → 1,1-diphenyl-O-acetylvinylcarbinol (3848-50-8)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / 0 - 20 °C

2: 1.70 g / 4-dimethylaminopyridine; Et₃N / 1,2-dichloro-ethane / 80 °C

With dmap; triethylamine; In tetrahydrofuran; 1,2-dichloro-ethane;

DOI:10.1021/ol070843w

Reference yield:

benzophenone (119-61-9) → 1,1-diphenyl-O-acetylvinylcarbinol (3848-50-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) Li/NH₃ liq. / 1.) -78 deg C, 2.) ether

2: 95 percent / H₂ / 10percent Pd/C / ethanol

3: 50 percent / KOH / 3 h / Heating

With potassium hydroxide; ammonia; hydrogen; lithium; palladium on activated charcoal; In ethanol;

DOI:10.1007/BF00758309

upstream raw materials:

1,1-diphenylprop-2-en-1-ol

acetic anhydride

benzophenone

1,1-diphenyl-2-propyn-1-ol

Downstream raw materials:

N-(1,1-diphenyl-2-propenyl)aniline

N-benzyl-1,1-diphenylprop-2-en-1-amine

3,3-diphenylacrylonitrile

1,1-diphenyl-1-acetoxy-2,3-dibromopropane

Refernces

• 1、 Yakhontov,Kutina,Shishkin,Zhikhareva,Vysochin,Vorob'eva,Kaminka,Shevchenko,Mashkovskii. "Synthesis of a 4-aza analog of phencarol and its pharmacological investigation". . p. 24 - 30. Retrieved 2007/10/02.