C₂₆H₂₆N₆O₂

Base Information

• Chemical Name: C₂₆H₂₆N₆O₂
• CAS No.: 1346242-88-3
• Molecular Formula: C₂₆H₂₆N₆O₂
• Molecular Weight: 454.531
• Mol file: 1346242-88-3.mol

Synonyms:C₂₆H₂₆N₆O₂

Chemical Property of C₂₆H₂₆N₆O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₂₆N₆O₂

There total 13 articles about C₂₆H₂₆N₆O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.0%

3-Pyrroline (109-96-6,760178-50-5) + C23H25N5O5S (1346245-10-0) → C26H26N6O2 (1346242-88-3)

Guidance literature:

In acetonitrile; at 90 ℃; for 1.5h; microwave irradiation;

Reference yield:

7-bromo-2-chloroquinoxaline (89891-65-6) → C26H26N6O2 (1346242-88-3)

Guidance literature:

Multi-step reaction with 6 steps

1.1: sodium carbonate / triphenylphosphine; palladium diacetate / 1,2-dimethoxyethane; water / 4 h / Reflux

2.1: sodium t-butanolate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / 1,4-dioxane / 90 °C / Inert atmosphere

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 5 °C / Inert atmosphere

3.2: 5 - 20 °C / Inert atmosphere

4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 5 h / 20 °C

4.2: Cooling with ice

5.1: triethylamine / dichloromethane / 2 h / 5 - 20 °C / Inert atmosphere

6.1: acetonitrile / 1.5 h / 90 °C / microwave irradiation

With tetrabutyl ammonium fluoride; sodium hydride; sodium carbonate; triethylamine; sodium t-butanolate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; 1,2-dimethoxyethane; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; mineral oil;

Reference yield:

7‐bromo‐2‐(1‐methyl‐1H‐pyrazol‐4‐yl)quinoxaline (1083325-87-4) → C26H26N6O2 (1346242-88-3)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium t-butanolate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / 1,4-dioxane / 90 °C / Inert atmosphere

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 5 °C / Inert atmosphere

2.2: 5 - 20 °C / Inert atmosphere

3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 5 h / 20 °C

3.2: Cooling with ice

4.1: triethylamine / dichloromethane / 2 h / 5 - 20 °C / Inert atmosphere

5.1: acetonitrile / 1.5 h / 90 °C / microwave irradiation

With tetrabutyl ammonium fluoride; sodium hydride; triethylamine; sodium t-butanolate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In tetrahydrofuran; 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; acetonitrile; mineral oil;

upstream raw materials:

3.5-dimethoxyaniline

3-Pyrroline

C₂₃H₂₅N₅O₅S

7-bromo-1H-quinoxalin-2-one