(2S,3S,4R,5R,6R)-2-((S)-Azido-phenyl-methyl)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran

Base Information

• Chemical Name: (2S,3S,4R,5R,6R)-2-((S)-Azido-phenyl-methyl)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran
• CAS No.: 947589-42-6
• Molecular Formula: C₄₁H₄₁N₃O₅
• Molecular Weight: 655.794

Synonyms:(2S,3S,4R,5R,6R)-2-((S)-Azido-phenyl-methyl)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran

Chemical Property of (2S,3S,4R,5R,6R)-2-((S)-Azido-phenyl-methyl)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3S,4R,5R,6R)-2-((S)-Azido-phenyl-methyl)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran

There total 11 articles about (2S,3S,4R,5R,6R)-2-((S)-Azido-phenyl-methyl)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

(R)-Phenyl-((2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-methanol (136034-22-5) → (2S,3S,4R,5R,6R)-2-((S)-Azido-phenyl-methyl)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran (947589-42-6)

Guidance literature:

With hydrogen azide; triphenylphosphine; diethylazodicarboxylate; In toluene; at 20 ℃; for 1h;

DOI:10.1039/b705750d

Reference yield:

phenylmagnesium bromide → (2S,3S,4R,5R,6R)-2-((S)-Azido-phenyl-methyl)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran (947589-42-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 66 percent / tetrahydrofuran / 3.5 h / -78 °C

2: 78 percent / hydrazoic acid; DEAD; triphenylphosphine / toluene / 1 h / 20 °C

With hydrogen azide; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene;

DOI:10.1039/b705750d

Reference yield:

2,3,4,6-tetra-O-benzyl-1-formyl-D-glucopyranose (113019-43-5,140397-45-1,140397-46-2,140397-47-3,140397-49-5,91738-17-9) → (2S,3S,4R,5R,6R)-2-((S)-Azido-phenyl-methyl)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran (947589-42-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 66 percent / tetrahydrofuran / 3.5 h / -78 °C

2: 78 percent / hydrazoic acid; DEAD; triphenylphosphine / toluene / 1 h / 20 °C

With hydrogen azide; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene;

DOI:10.1039/b705750d

upstream raw materials:

(R)-Phenyl-((2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-methanol

2,3,4,6-tetra-O-benzyl-1-formyl-D-glucopyranose

benzaldehyde dimethyl acetal

benzaldehyde

Downstream raw materials:

C₃₄H₃₅N₃O₅

[(S)-Phenyl-((2S,3S,4R,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-methyl]-carbamic acid tert-butyl ester

(2S,3R,4R,5S,6R)-2-((S)-Amino-phenyl-methyl)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol; compound with trifluoro-acetic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 947589-42-6 (2S,3S,4R,5R,6R)-2-((S)-Azido-phenyl-methyl)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran

Send

Send

Metric Ton KG G Pound L ML

Send

Send