2',3-Dihydroxy-4,4',6'-trimethoxychalcone

Base Information

Chemical Name:2',3-Dihydroxy-4,4',6'-trimethoxychalcone
CAS No.:121245-87-2
Molecular Formula:C₁₈H₁₈O₆
Molecular Weight:330.337
Hs Code.:
UNII:D83U9GSW4Z
DSSTox Substance ID:DTXSID201345754
Wikidata:Q76305885
Metabolomics Workbench ID:26802
ChEMBL ID:CHEMBL571087
Mol file:121245-87-2.mol

Synonyms:2',3-Dihydroxy-4,4',6'-trimethoxychalcone;3,2'-DIHYDROXY-4,4',6'-TRIMETHOXYCHALCONE;38186-71-9;(E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)prop-2-en-1-one;3,2//'-Dihydroxy-4,4//',6//'-trimethoxychalcone;1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-2-propen-1-one;2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-;RO 09-0444;D83U9GSW4Z;SPECTRUM1505153;CHEMBL571087;SCHEMBL2287800;WMOWJHFPSNZXSK-GQCTYLIASA-N;DTXSID201345754;LMPK12120327;AKOS024286707;CCG-214052;NCGC00096038-01;3,2/'-Dihydroxy-4,4/',6/'-trimethoxychalcone;AQ-358/42003065;Chalcone, 2',3-dihydroxy-4,4',6'-trimethoxy-;SR-05000002591;SR-05000002591-1;3,2'-Dihydroxy-4,4',6'-trimethoxychalcone, AldrichCPR;(2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-2-propen-1-one;(2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-2-propen-1-one #;2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-, (2E)-;Hydroxy-4,6-dimethoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-2-propen-1-one, 1-(2-

Suppliers and Price of 2',3-Dihydroxy-4,4',6'-trimethoxychalcone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2',3-Dihydroxy-4,4',6'-trimethoxychalcone

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:330.11033829
Heavy Atom Count:24
Complexity:437

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C=CC(=O)C2=C(C=C(C=C2OC)OC)O)O
Isomeric SMILES:COC1=C(C=C(C=C1)/C=C/C(=O)C2=C(C=C(C=C2OC)OC)O)O

Technology Process of 2',3-Dihydroxy-4,4',6'-trimethoxychalcone

There total 2 articles about 2',3-Dihydroxy-4,4',6'-trimethoxychalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 621-59-0
isovanillin

: 90-24-4
2-hydroxy-4,6-dimethoxyacetophenone

: 121245-87-2
(E)-1-(2′-hydroxy-4′,6′-dimethoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)prop-2-en-1-one

Guidance literature:: 2-hydroxy-4,6-dimethoxyacetophenone; With sodium hydroxide; In methanol; at 0 ℃; for 0.5h; Inert atmosphere;

isovanillin; In methanol; Inert atmosphere;
DOI:10.1016/j.ejmech.2020.112216

Reference yield:

: 108-73-6
3,5-dihydroxyphenol

: 121245-87-2
(E)-1-(2′-hydroxy-4′,6′-dimethoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)prop-2-en-1-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: boron trifluoride diethyl etherate / 50 °C / Inert atmosphere

2.1: potassium carbonate / acetone / 60 °C

2.2: 1 h / 60 °C

3.1: sodium hydroxide / methanol / 0.5 h / 0 °C / Inert atmosphere

3.2: Inert atmosphere

With boron trifluoride diethyl etherate; potassium carbonate; sodium hydroxide; In methanol; acetone;
DOI:10.1016/j.ejmech.2020.112216