5-N-tert-butoxycarbonylmethylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide

Base Information

Chemical Name:5-N-tert-butoxycarbonylmethylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide
CAS No.:1184301-87-8
Molecular Formula:C₂₆H₃₀N₂O₃
Molecular Weight:418.536
Hs Code.:

Synonyms:5-N-tert-butoxycarbonylmethylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide

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Chemical Property of 5-N-tert-butoxycarbonylmethylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide

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Technology Process of 5-N-tert-butoxycarbonylmethylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide

There total 2 articles about 5-N-tert-butoxycarbonylmethylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 165950-06-1
5-(((tert-butoxycarbonyl)amino)methyl)-2-methylbenzoic acid

: 3886-70-2
(R)-1-(1-Naphthyl)ethylamine

: 1184301-87-8
5-N-tert-butoxycarbonylmethylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 23 ℃; Combinatorial reaction / High throughput screening (HTS); Inert atmosphere;
DOI:10.1021/jm900611t

Reference yield: 91.0%

: 1184301-87-8
5-N-tert-butoxycarbonylmethylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide

Guidance literature:

Reference yield: 56.0%

: 1184301-87-8
5-N-tert-butoxycarbonylmethylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide

: 1184301-69-6
5-methylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide

Guidance literature:: 5-N-tert-butoxycarbonylmethylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide; With trifluoroacetic acid; In dichloromethane; at 23 ℃;

With sodium hydrogencarbonate; In water; Saturated solution;
DOI:10.1021/jm900611t