(Z)-7-<2-(6-methylheptyl)-1,3-dioxolan-2-yl>heptane-NNO-azoxy-2-ethene

Base Information

• Chemical Name: (Z)-7-<2-(6-methylheptyl)-1,3-dioxolan-2-yl>heptane-NNO-azoxy-2-ethene
• CAS No.: 119947-18-1
• Molecular Formula: C₂₀H₃₈N₂O₃
• Molecular Weight: 354.533
• Mol file: 119947-18-1.mol

Synonyms:(Z)-7-<2-(6-methylheptyl)-1,3-dioxolan-2-yl>heptane-NNO-azoxy-2-ethene

Chemical Property of (Z)-7-<2-(6-methylheptyl)-1,3-dioxolan-2-yl>heptane-NNO-azoxy-2-ethene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (Z)-7-<2-(6-methylheptyl)-1,3-dioxolan-2-yl>heptane-NNO-azoxy-2-ethene

There total 1 articles about (Z)-7-<2-(6-methylheptyl)-1,3-dioxolan-2-yl>heptane-NNO-azoxy-2-ethene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-bromo-6-methylheptane (52648-04-1) → (Z)-7-<2-(6-methylheptyl)-1,3-dioxolan-2-yl>heptane-NNO-azoxy-2-ethene (119947-18-1)

Guidance literature:

Multi-step reaction with 12 steps

1: 1.) Mg / 1.) ether, 2.) ether, 8 h, RT

2: 54 percent / I₂ / CHCl₃ / 2 h / Heating

3: 1.) O₃, 2.) LiAlH₄ / 1.) hexane, -45 deg C, 2.) hexane, ether, from -45 to -35 deg C

4: 94 percent / Br₂, NaHCO₃, HMPA / CH₂Cl₂ / 0 °C

5: 95 percent / TosOH*H₂O / toluene / 2 h / Heating

6: 90 percent / pyridine / 40 h / 4 °C

7: 1.) NaN₃, 2.) LiAlH₄ / 1.) N-methyl-2-pyrrolidinone, 3 h, 100 deg C, 2.) ether, 3 h

8: 98 percent / 2 h / Heating

9: N₂O₄, NaHCO₃ / diethyl ether / 1 h / 0 °C

10: 1.) t-BuOK, 2.) 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone / 1.) THF, 1 h, -30 deg C, 2.) THF, 16 h, RT

11: 1.) LDA / 1.) THF, 30 min, -78 deg C, 2.) THF, 30 min, -78 deg C

12: 1.) MsCl, Et₃N, 2.) Et₃N / 1.) toluene, 2 h, RT, 2.) toluene, 48 h, reflux

With pyridine; N,N,N,N,N,N-hexamethylphosphoric triamide; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; lithium aluminium tetrahydride; sodium azide; potassium tert-butylate; bromine; iodine; dinitrogen tetraoxide; sodium hydrogencarbonate; toluene-4-sulfonic acid; ozone; magnesium; methanesulfonyl chloride; triethylamine; lithium diisopropyl amide; In diethyl ether; dichloromethane; chloroform; toluene;

Reference yield: 86.0%

(Z)-7-<2-(6-methylheptyl)-1,3-dioxolan-2-yl>heptane-NNO-azoxy-2-ethene (119947-18-1) → jietacin A (109766-61-2)

Guidance literature:

With pyridinium p-toluenesulfonate; In acetone; for 2h; Heating;

upstream raw materials:

1-bromo-6-methylheptane

Downstream raw materials:

jietacin A