benzyl 4-<(tert-butyloxycarbonyl)amino>-1,3,5-trimethylpyrrole-2-carboxylate

Base Information

• Chemical Name: benzyl 4-<(tert-butyloxycarbonyl)amino>-1,3,5-trimethylpyrrole-2-carboxylate
• CAS No.: 75792-47-1
• Molecular Formula: C₂₀H₂₆N₂O₄
• Molecular Weight: 358.437

Synonyms:benzyl 4-<(tert-butyloxycarbonyl)amino>-1,3,5-trimethylpyrrole-2-carboxylate

Chemical Property of benzyl 4-<(tert-butyloxycarbonyl)amino>-1,3,5-trimethylpyrrole-2-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl 4-<(tert-butyloxycarbonyl)amino>-1,3,5-trimethylpyrrole-2-carboxylate

There total 8 articles about benzyl 4-<(tert-butyloxycarbonyl)amino>-1,3,5-trimethylpyrrole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzyl 4-isocyanato-1,3,5-trimethylpyrrole-2-carboxylate (75792-46-0) + tert-butyl alcohol (75-65-0) → benzyl 4-<(tert-butyloxycarbonyl)amino>-1,3,5-trimethylpyrrole-2-carboxylate (75792-47-1)

Guidance literature:

With copper(l) chloride; at 60 ℃; for 5h;

DOI:10.1021/jm00133a008

Reference yield:

ethyl 4-carboxy-1,3,5-trimethylpyrrole-2-carboxylate (7473-16-7) → benzyl 4-<(tert-butyloxycarbonyl)amino>-1,3,5-trimethylpyrrole-2-carboxylate (75792-47-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 100 percent / NaH / 90 °C / 10 Torr

2: 75 percent / diphenylphosphoryl azide (DPPA), Et₃N / acetonitrile / 1.5 h / 50 °C

3: 95 percent / CuCl / 5 h / 60 °C

With diphenylphosphoranyl azide; sodium hydride; triethylamine; copper(l) chloride; In acetonitrile;

DOI:10.1021/jm00133a008

Reference yield:

ethyl 4-isocyanato-1,3,5-trimethylpyrrole-2-carboxylate (75792-41-5) → benzyl 4-<(tert-butyloxycarbonyl)amino>-1,3,5-trimethylpyrrole-2-carboxylate (75792-47-1)

Guidance literature:

Multi-step reaction with 4 steps

1: Et₃N / acetonitrile / 5 h / 50 °C

2: H₂ / 10percent Pd/C / methanol

3: 100 percent / Na / 4 h / 100 °C

With hydrogen; sodium; triethylamine; palladium on activated charcoal; In methanol; acetonitrile;

DOI:10.1021/jm00133a008

upstream raw materials:

N-(tert-butyloxycarbonyl) azide

benzyl 4-amino-1,3,5-trimethylpyrrole-2-carboxylate

benzyl 4-isocyanato-1,3,5-trimethylpyrrole-2-carboxylate

tert-butyl alcohol

Downstream raw materials:

N-<5-<<(3-amino-3-iminopropyl)amino>carbonyl>-1,2,4-trimethylpyrrol-3-yl>-4-<<<4-(formylamino)-1,3,5-trimethylpyrrol-2-yl>carbonyl>amino>-1,3,5-trimethylpyrrole-2-carboxamide hydrochloride

N-<5-(benzyloxycarbonyl)-1,2,4-trimethylpyrrol-3-yl>-4-<<<4-<(tert-butyloxycarbonyl)amino>-1,3,5-trimethylpyrrol-2-yl>carbonyl>amino>-1,3,5-trimethylpyrrole-2-carboxamide

N-<5-(benzyloxycarbonyl)-1,2,4-trimethylpyrrol-3-yl>-4-<(tert-butyloxycarbonyl)amino>-1,3,5-trimethylpyrrole-2-carboxamide

4-<(tert-butyloxycarbonyl)amino>-1,3,5-trimethylpyrrole-2-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 75792-47-1 benzyl 4-<(tert-butyloxycarbonyl)amino>-1,3,5-trimethylpyrrole-2-carboxylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send