phenyl 4-O-acetyl-2-azido-3-O-chloroacetyl-2-deoxy-6-O-t-butyldiphenylsilyl-1-thio-β-D-galactopyranoside

Base Information

Chemical Name:phenyl 4-O-acetyl-2-azido-3-O-chloroacetyl-2-deoxy-6-O-t-butyldiphenylsilyl-1-thio-β-D-galactopyranoside
CAS No.:1447946-79-3
Molecular Formula:C₃₂H₃₆ClN₃O₆SSi
Molecular Weight:654.259
Hs Code.:

Synonyms:phenyl 4-O-acetyl-2-azido-3-O-chloroacetyl-2-deoxy-6-O-t-butyldiphenylsilyl-1-thio-β-D-galactopyranoside

Suppliers and Price of phenyl 4-O-acetyl-2-azido-3-O-chloroacetyl-2-deoxy-6-O-t-butyldiphenylsilyl-1-thio-β-D-galactopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of phenyl 4-O-acetyl-2-azido-3-O-chloroacetyl-2-deoxy-6-O-t-butyldiphenylsilyl-1-thio-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of phenyl 4-O-acetyl-2-azido-3-O-chloroacetyl-2-deoxy-6-O-t-butyldiphenylsilyl-1-thio-β-D-galactopyranoside

There total 7 articles about phenyl 4-O-acetyl-2-azido-3-O-chloroacetyl-2-deoxy-6-O-t-butyldiphenylsilyl-1-thio-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1447946-78-2
phenyl 4-O-acetyl-2-azido-2-deoxy-6-O-t-butyldiphenylsilyl-1-thio-β-D-galactopyranoside

: 79-04-9
chloroacetyl chloride

: 1447946-79-3
phenyl 4-O-acetyl-2-azido-3-O-chloroacetyl-2-deoxy-6-O-t-butyldiphenylsilyl-1-thio-β-D-galactopyranoside

Guidance literature:: With pyridine; In dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;
DOI:10.1039/c3ob40935j

Reference yield:

: 77481-63-1
phenyl-1-thio-β-D-mannopyranoside

: 1447946-79-3
phenyl 4-O-acetyl-2-azido-3-O-chloroacetyl-2-deoxy-6-O-t-butyldiphenylsilyl-1-thio-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 6 steps

1.1: pyridine / 12 h / Inert atmosphere

2.1: dimethyltin dichloride; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 0.03 h / Inert atmosphere

2.2: 1.5 h / 20 °C / Inert atmosphere

3.1: pyridine / dichloromethane / 2 h / 10 °C / Inert atmosphere

4.1: tetrabutylammoniun azide / acetonitrile / 20 h / -30 °C / Inert atmosphere

5.1: water / acetonitrile / 1 h / 65 °C / Inert atmosphere

6.1: pyridine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

With pyridine; water; dimethyltin dichloride; tetrabutylammoniun azide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; acetonitrile;
DOI:10.1039/c3ob40935j

Reference yield:

: 246875-56-9
phenyl 6-O-tert-butyldiphenylsilyl-1-thio-β-D-mannopyranoside

: 1447946-79-3
phenyl 4-O-acetyl-2-azido-3-O-chloroacetyl-2-deoxy-6-O-t-butyldiphenylsilyl-1-thio-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 5 steps

1.1: dimethyltin dichloride; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 0.03 h / Inert atmosphere

1.2: 1.5 h / 20 °C / Inert atmosphere

2.1: pyridine / dichloromethane / 2 h / 10 °C / Inert atmosphere

3.1: tetrabutylammoniun azide / acetonitrile / 20 h / -30 °C / Inert atmosphere

4.1: water / acetonitrile / 1 h / 65 °C / Inert atmosphere

5.1: pyridine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

With pyridine; water; dimethyltin dichloride; tetrabutylammoniun azide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; acetonitrile;
DOI:10.1039/c3ob40935j