N-<4-(2-<4-azido-2-hydroxybenzamido>ethyl)benzenesulfonyl>-N'-cyclohexylurea

Base Information

• Chemical Name: N-<4-(2-<4-azido-2-hydroxybenzamido>ethyl)benzenesulfonyl>-N'-cyclohexylurea
• CAS No.: 158435-38-2
• Molecular Formula: C₂₂H₂₆N₆O₅S
• Molecular Weight: 486.552
• Mol file: 158435-38-2.mol

Synonyms:N-<4-(2-<4-azido-2-hydroxybenzamido>ethyl)benzenesulfonyl>-N'-cyclohexylurea

Chemical Property of N-<4-(2-<4-azido-2-hydroxybenzamido>ethyl)benzenesulfonyl>-N'-cyclohexylurea

Chemical Property:

Purity/Quality:

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Technology Process of N-<4-(2-<4-azido-2-hydroxybenzamido>ethyl)benzenesulfonyl>-N'-cyclohexylurea

There total 1 articles about N-<4-(2-<4-azido-2-hydroxybenzamido>ethyl)benzenesulfonyl>-N'-cyclohexylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

N-(4-[2-amino-ethyl]-benzenesulfonyl)-N'-cyclohexyl urea (2015-16-9) + 4-azidosalicylic acid N-hydroxysuccinimide ester → N-<4-(2-<4-azido-2-hydroxybenzamido>ethyl)benzenesulfonyl>-N'-cyclohexylurea (158435-38-2)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 0 - 20 ℃;

DOI:10.1002/jlcr.2580340713

Reference yield: 11.0%

N-<4-(2-<4-azido-2-hydroxybenzamido>ethyl)benzenesulfonyl>-N'-cyclohexylurea (158435-38-2) → N-<4-(2-<4-azido-2-hydroxy-5-iodobenzamido>ethyl)benzenesulfonyl>-N'-cyclohexylurea + N-<4-(2-<4-azido-2-hydroxy-3,5-diiodobenzamido>ethyl)benzenesulfonyl>-N'-cyclohexylurea

Guidance literature:

With chloroamine-T; sodium iodide; In N,N-dimethyl-formamide; for 1h; Ambient temperature;

DOI:10.1002/jlcr.2580340713

Reference yield:

N-<4-(2-<4-azido-2-hydroxybenzamido>ethyl)benzenesulfonyl>-N'-cyclohexylurea (158435-38-2) → N-<4-(2-<4-azido-2-hydroxy-5-<125>iodobenzamido>ethyl)benzenesulfonyl>-N'-cyclohexylurea + C22H24(125)I2N6O5S

Guidance literature:

With sodium hydroxide; sodium (12?I)iodide; sodium phosphate buffer; chloroamine-T; for 0.25h; Ambient temperature;

DOI:10.1002/jlcr.2580340713

upstream raw materials:

N-(4-[2-amino-ethyl]-benzenesulfonyl)-N'-cyclohexyl urea