C₄₃H₆₀O₄Si₂

Base Information

• Chemical Name: C₄₃H₆₀O₄Si₂
• CAS No.: 250328-37-1
• Molecular Formula: C₄₃H₆₀O₄Si₂
• Molecular Weight: 697.118
• Mol file: 250328-37-1.mol

Synonyms:C₄₃H₆₀O₄Si₂

Chemical Property of C₄₃H₆₀O₄Si₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₃H₆₀O₄Si₂

There total 13 articles about C₄₃H₆₀O₄Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C36H56O3Si2 + benzoic acid anhydride (93-97-0) → C43H60O4Si2 (250328-37-1)

Guidance literature:

With dmap;

DOI:10.1021/ol990829m

Reference yield:

C28H46O4Si3 → C43H60O4Si2 (250328-37-1)

Guidance literature:

Multi-step reaction with 8 steps

1.1: 66 percent / trimethylsilyl triflate; 2,6-di-tert-butyl-4-methylpyridine / CH₂Cl₂ / -78 - 6 °C

2.1: DIBAL / -78 °C

2.2: 77 percent / 4-(dimethylamino)pyridine

3.1: 73 percent / ZnI₂

4.1: 93 percent / m-CPBA

5.1: 90 percent / dimethylaluminum chloride

6.1: 91 percent / NaBH₄

7.1: 99 percent / 4-(dimethylamino)pyridine

With dmap; sodium tetrahydroborate; 2,6-di-tert-butyl-4-methylpyridine; trimethylsilyl trifluoromethanesulfonate; dimethylaluminum chloride; diisobutylaluminium hydride; 3-chloro-benzenecarboperoxoic acid; zinc(II) iodide; In dichloromethane; 6.1: Petasis-Ferrier rearrangement;

DOI:10.1021/ol990829m

Reference yield:

3-(tert-butyldiphenylsilyloxy)-1-propanal (112897-03-7) → C43H60O4Si2 (250328-37-1)

Guidance literature:

Multi-step reaction with 11 steps

1.1: triethylamine; Bu₂BOTf

2.1: LiOH; H₂O₂

3.1: CH₂Cl₂ / 20 °C

4.1: 66 percent / trimethylsilyl triflate; 2,6-di-tert-butyl-4-methylpyridine / CH₂Cl₂ / -78 - 6 °C

5.1: DIBAL / -78 °C

5.2: 77 percent / 4-(dimethylamino)pyridine

6.1: 73 percent / ZnI₂

7.1: 93 percent / m-CPBA

8.1: 90 percent / dimethylaluminum chloride

9.1: 91 percent / NaBH₄

10.1: 99 percent / 4-(dimethylamino)pyridine

With dmap; lithium hydroxide; sodium tetrahydroborate; 2,6-di-tert-butyl-4-methylpyridine; trimethylsilyl trifluoromethanesulfonate; di-n-butylboryl trifluoromethanesulfonate; dihydrogen peroxide; dimethylaluminum chloride; diisobutylaluminium hydride; triethylamine; 3-chloro-benzenecarboperoxoic acid; zinc(II) iodide; In dichloromethane; 9.1: Petasis-Ferrier rearrangement;

DOI:10.1021/ol990829m

upstream raw materials:

benzoic acid anhydride

(2R,4R,5S)-4-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-6-eth-(E)-ylidene-5-methyl-2-[(triisopropylsilanyl)-ethynyl]-[1,3]dioxane

(2R,4R,5S)-4-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-6-eth-(Z)-ylidene-5-methyl-2-[(triisopropylsilanyl)-ethynyl]-[1,3]dioxane

Acetic acid (2R,4S,5S,6R)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-5-methyl-2-[(triisopropylsilanyl)-ethynyl]-[1,3]dioxan-4-yl ester

Downstream raw materials:

C₁₈H₂₂O₄