3-azido-5-azidomethylbenzoic acid methyl ester

Base Information

• Chemical Name: 3-azido-5-azidomethylbenzoic acid methyl ester
• CAS No.: 1310822-76-4
• Molecular Formula: C₉H₈N₆O₂
• Molecular Weight: 232.202
• Mol file: 1310822-76-4.mol

Synonyms:3-azido-5-azidomethylbenzoic acid methyl ester

Chemical Property of 3-azido-5-azidomethylbenzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-azido-5-azidomethylbenzoic acid methyl ester

There total 9 articles about 3-azido-5-azidomethylbenzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.4%

methyl 3-azido-5-(bromomethyl)benzoate (1620809-41-7) → 3-azido-5-azidomethylbenzoic acid methyl ester (1310822-76-4)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1002/ejoc.201402516

Reference yield: 92.0%

3-azido-5-hydroxymethylbenzoic acid methyl ester (1310822-75-3) → 3-azido-5-azidomethylbenzoic acid methyl ester (1310822-76-4)

Guidance literature:

With dmap; sodium azide; bis(2,4-dichlorodiphenyl) phosphorochloridate; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

DOI:10.1021/jm2001025

Reference yield: 65.0%

methyl 3-(azidomethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (1443655-57-9) → 3-azido-5-azidomethylbenzoic acid methyl ester (1310822-76-4)

Guidance literature:

With sodium azide; copper diacetate; In methanol; at 55 ℃; for 0.666667h; Microwave irradiation;

DOI:10.1080/00397911.2012.697595

upstream raw materials:

3-azido-5-hydroxymethylbenzoic acid methyl ester

dimethyl 5-aminoisophthalate

3-Amino-5-hydroxymethylbenzoic acid methyl ester

1-methoxycarbonyl-3-methylbenzene

Downstream raw materials:

3-azido-5-(azidomethyl)-benzoic acid

7-({5-[4-(3-azido-5-azidomethylbenzoylamino)phenyl]isoxazole-3-carbonyl}amino)heptanoic acid methyl ester

7-{1-[4-(3-azido-5-azidomethylbenzoylamino)benzyl]-1H-pyrazol-4-ylcarbamoyl}heptanoic acid methyl ester

5-[4-(3-azido-5-azidomethylbenzoylamino)phenyl]isoxazole-3-carboxylic acid (6-hydroxycarbamoylhexyl)amide