N-carbobenzyloxy-L-alanyl-N-(2,3-dihydro-1H-inden-5-yl)glycine ethyl ester

Base Information

Chemical Name:N-carbobenzyloxy-L-alanyl-N-(2,3-dihydro-1H-inden-5-yl)glycine ethyl ester
CAS No.:84827-41-8
Molecular Formula:C₂₄H₂₈N₂O₅
Molecular Weight:424.497
Hs Code.:

Synonyms:N-carbobenzyloxy-L-alanyl-N-(2,3-dihydro-1H-inden-5-yl)glycine ethyl ester

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Chemical Property of N-carbobenzyloxy-L-alanyl-N-(2,3-dihydro-1H-inden-5-yl)glycine ethyl ester

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Technology Process of N-carbobenzyloxy-L-alanyl-N-(2,3-dihydro-1H-inden-5-yl)glycine ethyl ester

There total 2 articles about N-carbobenzyloxy-L-alanyl-N-(2,3-dihydro-1H-inden-5-yl)glycine ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 1142-20-7
N-Cbz-Ala

: 84827-40-7
N-(2,3-dihydro-1H-inden-5-yl)glycine ethyl ester

: 84827-41-8
N-carbobenzyloxy-L-alanyl-N-(2,3-dihydro-1H-inden-5-yl)glycine ethyl ester

Guidance literature:: With dicyclohexyl-carbodiimide; In dichloromethane; 0 deg C, 0.2 h, room temp., overnight;

Reference yield:

: 24425-40-9
indan-5-amine

: 84827-41-8
N-carbobenzyloxy-L-alanyl-N-(2,3-dihydro-1H-inden-5-yl)glycine ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / triethylamine / ethanol / 50 °C

2: 68 percent / dicyclohexylcarbodiimide / CH₂Cl₂ / 0 deg C, 0.2 h, room temp., overnight

With triethylamine; dicyclohexyl-carbodiimide; In ethanol; dichloromethane;