(1S,4R,6R,8R)-11,11-dimethyl-4-(E)-styryl-5-oxa-3-thiatricyclo[6.2.1.0^1,6]undecane

Base Information

• Chemical Name: (1S,4R,6R,8R)-11,11-dimethyl-4-(E)-styryl-5-oxa-3-thiatricyclo[6.2.1.0^1,6]undecane
• CAS No.: 113124-75-7
• Molecular Formula: C₁₉H₂₄OS
• Molecular Weight: 300.465
• Mol file: 113124-75-7.mol

Synonyms:(1S,4R,6R,8R)-11,11-dimethyl-4-(E)-styryl-5-oxa-3-thiatricyclo[6.2.1.0^1,6]undecane

Chemical Property of (1S,4R,6R,8R)-11,11-dimethyl-4-(E)-styryl-5-oxa-3-thiatricyclo[6.2.1.0^1,6]undecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S,4R,6R,8R)-11,11-dimethyl-4-(E)-styryl-5-oxa-3-thiatricyclo[6.2.1.0^1,6]undecane

There total 2 articles about (1S,4R,6R,8R)-11,11-dimethyl-4-(E)-styryl-5-oxa-3-thiatricyclo[6.2.1.0^1,6]undecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(E)-3-phenylpropenal (14371-10-9) + (1R,2S,4S)-1-Mercaptomethyl-7,7-dimethyl-bicyclo[2.2.1]heptan-2-ol → (1S,4R,6R,8R)-11,11-dimethyl-4-(E)-styryl-5-oxa-3-thiatricyclo[6.2.1.01,6]undecane (113124-75-7) + (1S,4R,6R,8R)-11,11-dimethyl-4-(Z)-styryl-5-oxa-3-thiatricyclo[6.2.1.01,6]undecane

Guidance literature:

With pyridinium p-toluenesulfonate; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1039/b206857e

Reference yield: 98.0%

(E)-3-phenylpropenal (14371-10-9) + (1S,2R,4R)-(-)-10-mercaptoisoboneol (71242-58-5) → (1S,4R,6R,8R)-11,11-dimethyl-4-(E)-styryl-5-oxa-3-thiatricyclo[6.2.1.01,6]undecane (113124-75-7) + (1S,4R,6R,8R)-11,11-dimethyl-4-(Z)-styryl-5-oxa-3-thiatricyclo[6.2.1.01,6]undecane

Guidance literature:

With pyridinium p-toluenesulfonate; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1039/b206857e

Reference yield: 95.0%

dichloroacethyl chloride (79-36-7) + (1S,4R,6R,8R)-11,11-dimethyl-4-(E)-styryl-5-oxa-3-thiatricyclo[6.2.1.01,6]undecane (113124-75-7) → (1S,6S,10R,12R)-5,5-dichloro-15,15-dimethyl-6-phenyl-9-oxa-3-thia-tricyclo[8.4.0.11,12]pentadec-7-(E)-en-4-one

Guidance literature:

With triethylamine; In hexane; at 20 ℃; for 1.8h;

DOI:10.1039/b206857e

upstream raw materials:

(E)-3-phenylpropenal

(1S,2R,4R)-(-)-10-mercaptoisoboneol

Downstream raw materials:

(1R,2S)-1-((1S,4R,6R,8R)-11,11-Dimethyl-5-oxa-3-thia-tricyclo[6.2.1.0^1,6]undec-4-yl)-2-phenyl-ethane-1,2-diol

(1S,2R)-1-((1S,4R,6R,8R)-11,11-Dimethyl-5-oxa-3-thia-tricyclo[6.2.1.0^1,6]undec-4-yl)-2-phenyl-ethane-1,2-diol

(1R,2R)-1-phenylpropane-1,2,3-triol