C₇₀H₆₉Cl₄N₃O₂₀

Base Information

• Chemical Name: C₇₀H₆₉Cl₄N₃O₂₀
• CAS No.: 1013038-29-3
• Molecular Formula: C₇₀H₆₉Cl₄N₃O₂₀
• Molecular Weight: 1414.14
• Mol file: 1013038-29-3.mol

Synonyms:C₇₀H₆₉Cl₄N₃O₂₀

Chemical Property of C₇₀H₆₉Cl₄N₃O₂₀

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₇₀H₆₉Cl₄N₃O₂₀

There total 10 articles about C₇₀H₆₉Cl₄N₃O₂₀ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

C68H69ClN2O20 (949000-11-7) + trichloroacetonitrile (545-06-2) → C70H69Cl4N3O20 (1013038-29-3)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 0 ℃; for 0.166667h;

DOI:10.1021/jo070669p

Reference yield:

p-methoxyphenyl 3,6-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranoside (129575-89-9) → C70H69Cl4N3O20 (1013038-29-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / N-(phenylthio)-ε-caprolactam; Tf2O; 4 Angstroem molecular sieves / CH2Cl2 / 0.75 h / -20 °C

2: 89 percent / CAN / acetonitrile; H₂O; toluene / 0.33 h / 0 °C

3: 92 percent / DBU / CH₂Cl₂ / 0.17 h / 0 °C

With N-(phenylthio)-ε-caprolactam; ammonium cerium(IV) nitrate; trifluoromethylsulfonic anhydride; 4 A molecular sieve; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; water; toluene; acetonitrile;

DOI:10.1021/jo070669p

Reference yield:

N-benzyl-2-amino-6-O-benzyl-2,3-N,O-carbonyl-4-O-chloroacetyl-2-deoxy-α-D-glucopyranosyl bromide (910805-67-3) → C70H69Cl4N3O20 (1013038-29-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 56 percent / 2,6-di-tert-butyl-4-methylpyridine; AgOTf; molecular sieves 4 Angstroem / dioxane; toluene / 24 h / 0 - 20 °C

2: 75 percent / N-(phenylthio)-ε-caprolactam; Tf2O; 4 Angstroem molecular sieves / CH2Cl2 / 0.75 h / -20 °C

3: 89 percent / CAN / acetonitrile; H₂O; toluene / 0.33 h / 0 °C

4: 92 percent / DBU / CH₂Cl₂ / 0.17 h / 0 °C

With N-(phenylthio)-ε-caprolactam; 2,6-di-tert-butyl-4-methylpyridine; ammonium cerium(IV) nitrate; trifluoromethylsulfonic anhydride; 4 A molecular sieve; silver trifluoromethanesulfonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In 1,4-dioxane; dichloromethane; water; toluene; acetonitrile;

DOI:10.1021/jo070669p

upstream raw materials:

C₆₈H₆₉ClN₂O₂₀

trichloroacetonitrile

N-benzyl-2-amino-6-O-benzyl-2,3-N,O-carbonyl-4-O-chloroacetyl-2-deoxy-α-D-glucopyranosyl bromide

C₇₅H₇₅ClN₂O₂₁