(E)-3-(1-((4-methoxyphenethyl)amino)-2,3-dihydro-1H-inden-5-yl)propenoic acid methyl ester

Base Information

Chemical Name:(E)-3-(1-((4-methoxyphenethyl)amino)-2,3-dihydro-1H-inden-5-yl)propenoic acid methyl ester
CAS No.:786650-72-4
Molecular Formula:C₂₂H₂₅NO₃
Molecular Weight:351.445
Hs Code.:

Synonyms:(E)-3-(1-((4-methoxyphenethyl)amino)-2,3-dihydro-1H-inden-5-yl)propenoic acid methyl ester

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Chemical Property of (E)-3-(1-((4-methoxyphenethyl)amino)-2,3-dihydro-1H-inden-5-yl)propenoic acid methyl ester

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Technology Process of (E)-3-(1-((4-methoxyphenethyl)amino)-2,3-dihydro-1H-inden-5-yl)propenoic acid methyl ester

There total 3 articles about (E)-3-(1-((4-methoxyphenethyl)amino)-2,3-dihydro-1H-inden-5-yl)propenoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 786647-54-9
methyl (2E)-3-(1-oxo-2,3-dihydro-1H-inden-5-yl)-2-propenoate

: 55-81-2
4-Methoxyphenethylamine

: 786650-72-4
(E)-3-(1-((4-methoxyphenethyl)amino)-2,3-dihydro-1H-inden-5-yl)propenoic acid methyl ester

Guidance literature:: With toluene-4-sulfonic acid; In toluene; at 130 ℃; for 3h;

Reference yield:

: 34598-49-7
5-Bromo-1-indanone

: 786650-72-4
(E)-3-(1-((4-methoxyphenethyl)amino)-2,3-dihydro-1H-inden-5-yl)propenoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; triphenylphosphine; palladium diacetate / N,N-dimethyl-formamide / 100 °C

2: toluene-4-sulfonic acid / toluene / 3 h / 130 °C

With palladium diacetate; toluene-4-sulfonic acid; triethylamine; triphenylphosphine; In N,N-dimethyl-formamide; toluene;