5-Oxo-15-hete

Base Information

Chemical Name:5-Oxo-15-hete
CAS No.:142828-12-4
Molecular Formula:C₂₀H₃₀O₄
Molecular Weight:334.456
Hs Code.:
DSSTox Substance ID:DTXSID201158737
Wikidata:Q27073999
Pharos Ligand ID:B1XMVH2UYU5M
ChEMBL ID:CHEMBL1682258
Mol file:142828-12-4.mol

Synonyms:5-oxo-15-HETE;5-oxo-15-hydroxy-6,8,11,13-eicosatetraenoic acid

Suppliers and Price of 5-Oxo-15-hete

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 5-Oxo-15-hete

Chemical Property:

Vapor Pressure:3.35E-14mmHg at 25°C
Boiling Point:546.1°C at 760 mmHg
Flash Point:298.1°C
PSA：74.60000
Density:1.036g/cm³
LogP:4.36650
XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:14
Exact Mass:334.21440943
Heavy Atom Count:24
Complexity:458

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCCCC(C=CC=CCC=CC=CC(=O)CCCC(=O)O)O
Isomeric SMILES:CCCCC[C@@H](/C=C/C=C\C/C=C\C=C\C(=O)CCCC(=O)O)O

Technology Process of 5-Oxo-15-hete

There total 11 articles about 5-Oxo-15-hete which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1295575-62-0
methyl 15-hydroxy-5-oxo-eicosa-6(E),8(Z),11(Z),13(E)-tetraenoate

: 142828-12-4
5-Oxo-15-HETE

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 3h;
DOI:10.1016/j.bmcl.2011.01.032

Reference yield:

: 1295575-56-2
7-(tert-butyldimethylsilanyloxy)-1-tributylsilanyloxy-dodeca-3,5-diene

: 142828-12-4
5-Oxo-15-HETE

Guidance literature:: Multi-step reaction with 7 steps

1.1: acetic acid / tetrahydrofuran; water / 8 h / 20 °C

2.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h / 0 °C

3.1: acetonitrile / 48 h / 65 °C

4.1: n-butyllithium / tetrahydrofuran / 0.5 h / 0 °C

4.2: -78 - 20 °C

5.1: bis-[(trifluoroacetoxy)iodo]benzene / methanol; water / 0.03 h / 20 °C / Inert atmosphere

6.1: water; pyridinium p-toluenesulfonate / tetrahydrofuran; methanol / 48 h / 20 °C / Inert atmosphere

7.1: water; lithium hydroxide / tetrahydrofuran / 3 h / 20 °C

With 1H-imidazole; n-butyllithium; water; iodine; pyridinium p-toluenesulfonate; acetic acid; triphenylphosphine; bis-[(trifluoroacetoxy)iodo]benzene; lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water; acetonitrile;
DOI:10.1016/j.bmcl.2011.01.032

Reference yield:

: 1295575-57-3
7-(tert-butyldimethylsilanyloxy)dodeca-3,5-dienol

: 142828-12-4
5-Oxo-15-HETE

Guidance literature:: Multi-step reaction with 6 steps

1.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h / 0 °C

2.1: acetonitrile / 48 h / 65 °C

3.1: n-butyllithium / tetrahydrofuran / 0.5 h / 0 °C

3.2: -78 - 20 °C

4.1: bis-[(trifluoroacetoxy)iodo]benzene / methanol; water / 0.03 h / 20 °C / Inert atmosphere

5.1: water; pyridinium p-toluenesulfonate / tetrahydrofuran; methanol / 48 h / 20 °C / Inert atmosphere

6.1: water; lithium hydroxide / tetrahydrofuran / 3 h / 20 °C

With 1H-imidazole; n-butyllithium; water; iodine; pyridinium p-toluenesulfonate; triphenylphosphine; bis-[(trifluoroacetoxy)iodo]benzene; lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water; acetonitrile;
DOI:10.1016/j.bmcl.2011.01.032