Technology Process of 7-methyl-5-(phenyloxycarbonyl)oxy-3-(3-trifluoromethylphenyl)-5,6,7,8-tetrahydrocinnoline
There total 5 articles about 7-methyl-5-(phenyloxycarbonyl)oxy-3-(3-trifluoromethylphenyl)-5,6,7,8-tetrahydrocinnoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sodium tetrahydroborate / ethanol / 1 h / 0 - 20 °C
2: pyridine / toluene / 20 °C
With
pyridine; sodium tetrahydroborate;
In
ethanol; toluene;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: pyridinium perbromide hydrobromide / toluene / 5 h / 0 - 20 °C
1.2: 0 °C
2.1: potassium carbonate / chloroform / 20 °C
2.2: 0 °C
3.1: hydrazine hydrochloride; triethylamine / ethanol / 3 h / 20 °C
4.1: toluene-4-sulfonic acid / pyridine / 72 h / 20 °C
5.1: sodium tetrahydroborate / ethanol / 1 h / 0 - 20 °C
6.1: pyridine / toluene / 20 °C
With
pyridine; sodium tetrahydroborate; pyridinium perbromide hydrobromide; hydrazine hydrochloride; potassium carbonate; toluene-4-sulfonic acid; triethylamine;
In
pyridine; ethanol; chloroform; toluene;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate / chloroform / 20 °C
1.2: 0 °C
2.1: hydrazine hydrochloride; triethylamine / ethanol / 3 h / 20 °C
3.1: toluene-4-sulfonic acid / pyridine / 72 h / 20 °C
4.1: sodium tetrahydroborate / ethanol / 1 h / 0 - 20 °C
5.1: pyridine / toluene / 20 °C
With
pyridine; sodium tetrahydroborate; hydrazine hydrochloride; potassium carbonate; toluene-4-sulfonic acid; triethylamine;
In
pyridine; ethanol; chloroform; toluene;
