2003-10-3

Basic information

• Product Name: 3-(TRIFLUOROMETHYL)PHENACYL BROMIDE
• Synonyms: 3-(TRIFLUOROMETHYL)PHENACYL BROMIDE;2-BROMO-1-[3-(TRIFLUOROMETHYL)PHENYL]-1-ETHANONE;2-BROMO-1-(3-TRIFLUOROMETHYL-PHENYL)-ETHANONE;BUTTPARK 35\01-54;2-Bromo-1-[3-(trifluoromethyl)phenyl]-1-ethanone, tech;2-Bromo-3'-(trifluoromethyl)acetophenone;2-Bromo-1-(3-(trifluoromethyl)phenyl)ethanone ,97%;2-Bromo-3'-(trifluoromethyl)acetophenone, 2-Bromo-1-[3-(trifluoromethyl)phenyl]ethan-1-one, 3-(Bromoacetyl)benzotrifluoride
• CAS NO: 2003-10-3
• Molecular Formula: C₉H₆BrF₃O
• Molecular Weight: 267.04
• Mol File: 2003-10-3.mol
• Article Data: 45

Chemical Properties

• Melting Point: 22°C
• Boiling Point: 64-72°C
• Flash Point: 94.373 °C
• Appearance: /
• Density: 1.593 g/cm³
• Vapor Pressure: 0.059mmHg at 25°C
• Refractive Index: 1.496
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 3-(TRIFLUOROMETHYL)PHENACYL BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(TRIFLUOROMETHYL)PHENACYL BROMIDE(2003-10-3)
• EPA Substance Registry System: 3-(TRIFLUOROMETHYL)PHENACYL BROMIDE(2003-10-3)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: 1760
• Hazardous Substances Data: 2003-10-3(Hazardous Substances Data)

Usage

General Description

3-(Trifluoromethyl)phenacyl bromide is a chemical compound with the molecular formula C10H7BrF3O. It is primarily used as a reagent in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. The compound contains a trifluoromethyl group, which enhances its reactivity and selectivity in various chemical reactions. It is known for its ability to undergo nucleophilic substitution reactions, and it is often used as a key intermediate in the synthesis of complex organic molecules. Additionally, 3-(Trifluoromethyl)phenacyl bromide has the potential to be used as a building block in the development of new materials and functional polymers due to its unique chemical properties.

InChI:InChI=1/C9H6BrF3O/c10-5-8(14)6-2-1-3-7(4-6)9(11,12)13/h1-4H,5H2

Upstream product

• 108773-81-5 3-Bromomethyl-4,4-dimethyl-3-(3-trifluoromethyl-phenyl)-[1,2]dioxetane 
• 349-76-8 3'-(trifluoromethyl)acetophenone 
• 402-24-4 3-(trifluoromethyl)styrene 
• 454-89-7 3-Trifluoromethylbenzaldehyde 

Downstream Products

• 159885-60-6 2-<4-carboethoxy-5-(trifluoromethyl)pyrazol-1-yl>-4-<3-(trifluoromethyl)phenyl>thiazole 
• 54669-74-8 2-(m-trifluoromethylphenacyl)cyclohexanone 
• 708984-73-0 3-hydroxy-5-methyl-2-[2-oxo-2-(3-trifluoromethylphenyl)-ethyl]-cyclohex-2-enone 
• 708984-71-8 3-hydroxy-2-[2-oxo-2-(3-trifluoromethylphenyl)ethyl]-5-phenylcyclohex-2-enone 
• 254910-93-5 methyl 4-[4-(3-trifluoromethylphenyl)-2-oxazolyl]benzoate 
• 254911-21-2 methyl 3-[4-(3-trifluoromethylphenyl)-2-thiazolyl]benzoate 
• 179419-39-7 2-Amidino-4-(3-trifluoromethylphenyl)thiazole Hydrobromide 
• 62368-85-8 2-(m-trifluoromethylphenacyl)cycloheptanone 
• 887625-71-0 2-thiocyanato-1-(3-trifluoromethylphenyl)ethanone 
• 1190236-33-9 {4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}methyl 2,2-dimethylpropanoate 
• 1190234-58-2 ethyl 1-({4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl}methyl)-1H-pyrazole-4-carboxylate 

Relevant articles and documents

Thiazole ring-containing amide compounds as well as preparation method and application thereof

The invention discloses thiazole ring-containing amide compounds as well as a preparation method and application thereof, and belongs to the field of chemical technologies and pesticides. According to the present invention, p-phenylenediamine is adopted as a raw material to synthesize a series of the thiazole ring-containing amide compounds, and the synthesized thiazole ring-containing amide compounds have good inhibition effects on Xanthomonas oryzae pv.Oryza (Xoo), Xanthomonas oryzae pv.Oryzcola (Xoc) and Xanthomonas axonophora pv.Citri (Xac) in agricultural diseases and insect pests, and can be used for preparing the anti-plant bacterium agent.

N-(1-CYANO-PYRROLIDIN-3-YL)-5-(3-(TRIFLUOROMETHYL)PHENYL)OXAZOLE-2-CARBOXAMIDE DERIVATIVES AND THE CORRESPONDING OXADIAZOLE DERIVATIVES AS USP30 INHIBITORS FOR THE TREATMENT OF MITOCHONDRIAL DYSFUNCTION

The present invention relates to a class of N-cyanopyrrolidines with activity as inhibitors of the deubiquitylating enzyme USP30, having utility in a variety of therapeutic areas, including conditions involving mitochondrial dysfunction, cancer and fibros

Nickel-catalyzed asymmetric arylative cyclization of N-alkynones: Efficient access to 1,2,3,6-tetrahydropyridines with a tertiary alcohol

Nickel/(S)-t-Bu-PHOX complex catalyzed asymmetric arylative cyclization of N-alkynones has been achieved, delivering 1,2,3,6-tetrahydropyridines containing a chiral tertiary alcohol in high yields and excellent enantioselectivities, which provides efficient access to chiral tetrahydropyridine and piperidine analogues.