2-Piperidinecarboxylic acid, 1-acetyl-, (2S)- (9CI)

Base Information

Chemical Name:2-Piperidinecarboxylic acid, 1-acetyl-, (2S)- (9CI)
CAS No.:111555-81-8
Molecular Formula:C8H13 N O3
Molecular Weight:171.196
Hs Code.:
Mol file:111555-81-8.mol

Synonyms:2-Piperidinecarboxylicacid, 1-acetyl-, (S)-; (2S)-N-Acetyl-2-piperidinecarboxylic acid;N-Acetyl-L-pipecolic acid

Suppliers and Price of 2-Piperidinecarboxylic acid, 1-acetyl-, (2S)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 7 raw suppliers

Chemical Property of 2-Piperidinecarboxylic acid, 1-acetyl-, (2S)- (9CI)

Chemical Property:

Boiling Point:374.0±35.0 °C(Predicted)
PKA:3.70±0.20(Predicted)
PSA：57.61000
Density:1.213±0.06 g/cm3(Predicted)
LogP:0.40990

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Piperidinecarboxylic acid, 1-acetyl-, (2S)- (9CI)

There total 3 articles about 2-Piperidinecarboxylic acid, 1-acetyl-, (2S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 108-24-7
acetic anhydride

: 3105-95-1,83680-83-5
pipecolinic acid

: 111555-81-8
(S)-1-acetylpiperidine-2-carboxylic acid

Guidance literature:: With sodium hydrogencarbonate; In tetrahydrofuran; water; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1016/j.chembiol.2018.02.013

Reference yield:

: 111479-14-2
methyl dl-N-acetylpipecolate

: 178963-27-4
(R)-1-acetylpiperidine-2-carboxylic acid

: 111555-81-8
(S)-1-acetylpiperidine-2-carboxylic acid

Guidance literature:: With sodium hydroxide; pig liver esterase; In water; for 240h; Product distribution; hydrolysis of other various esters;
DOI:10.1139/v87-452