2-Amino-2',5-dichlorobenzophenone

Base Information

Chemical Name:2-Amino-2',5-dichlorobenzophenone
CAS No.:2958-36-3
Deprecated CAS:53960-29-5
Molecular Formula:C13H9Cl2NO
Molecular Weight:266.127
Hs Code.:29223900
European Community (EC) Number:220-985-2
NSC Number:611905
UNII:G806VEO3KE
DSSTox Substance ID:DTXSID7062742
Nikkaji Number:J23.028F
Wikidata:Q27278905
ChEMBL ID:CHEMBL1488083
Mol file:2958-36-3.mol

Synonyms:2-amino-2',5-dichlorobenzophenone;ADB, benzophenone

Suppliers and Price of 2-Amino-2',5-dichlorobenzophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Amino-2’,5-dichlorobenzophenone
25g
$ 100.00

TRC
2-Amino-2’,5-dichlorobenzophenone
5g
$ 65.00

TCI Chemical
2-Amino-2',5-dichlorobenzophenone >98.0%(N)
10g
$ 12.00

SynQuest Laboratories
2-Amino-2',5-dichlorobenzophenone 99%
5 g
$ 16.00

Sigma-Aldrich
Lorazepam Related Compound B United States Pharmacopeia (USP) Reference Standard
25mg
$ 1160.00

Sigma-Aldrich
2-Amino-2′,5-dichlorobenzophenone 99%
50g
$ 152.00

Sigma-Aldrich
2-Amino-2′,5-dichlorobenzophenone 99%
10g
$ 32.00

Oakwood
2-Amino-2',5-dichlorobenzophenone 99%
10g
$ 50.00

Medical Isotopes, Inc.
2-Amino-2??,5-dichlorobenzophenone
25 g
$ 1380.00

Matrix Scientific
(2-Amino-5-chlorophenyl)-(2-chlorophenyl)methanone 98%
10g
$ 756.00

Total 111 raw suppliers

Chemical Property of 2-Amino-2',5-dichlorobenzophenone

Chemical Property:

Appearance/Colour:yellow to yellow-green powder
Vapor Pressure:0Pa at 25℃
Melting Point:87-89 °C(lit.)
Refractive Index:1.5490 (estimate)
Boiling Point:453.6 °C at 760 mmHg
PKA:-0.97±0.10(Predicted)
Flash Point:228.1 °C
PSA：43.09000
Density:1.373 g/cm³
LogP:4.38780
Storage Temp.:Refrigerator
Solubility.:methanol: soluble
Water Solubility.:Insoluble in water.
XLogP3:4.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:265.0061193
Heavy Atom Count:17
Complexity:285

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-2’,5-dichlorobenzophenone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi, Xn
Hazard Codes:Xi,Xn
Statements: 36/37/38-20/21/22
Safety Statements: 26-37/39-24/25-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)C2=C(C=CC(=C2)Cl)N)Cl
Uses 2-Amino-2',5-dichlorobenzophenone is used to produce lorazepam a drug of the benzodiazepine group, used especially to treat anxiety. Lorazepam Impurity A.

Technology Process of 2-Amino-2',5-dichlorobenzophenone

There total 18 articles about 2-Amino-2',5-dichlorobenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 77792-52-0
5-chloro-3-(2-chlorophenyl)-2,1-benzisoxazole

: 2958-36-3,53960-29-5
(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Guidance literature:: With iron; acetic acid; In ethanol; water; at 60 - 70 ℃; for 2h;
DOI:10.1135/cccc19803593

Reference yield: 52.0%

: 5922-60-1
2-amino-5-chlorobenzonitrile

: 3900-89-8
2-Chlorobenzeneboronic acid

: 2958-36-3,53960-29-5
(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

Guidance literature:: With 5,5'-dimethyl-2,2'-bipyridine; methanesulfonic acid; palladium(II) trifluoroacetate; water; In 2-methyltetrahydrofuran; at 80 ℃; for 36h; Schlenk technique;
DOI:10.1039/c4ob00978a