C₂₇H₂₈FN₃O₉S

Base Information

• Chemical Name: C₂₇H₂₈FN₃O₉S
• CAS No.: 1355034-97-7
• Molecular Formula: C₂₇H₂₈FN₃O₉S
• Molecular Weight: 589.598
• Mol file: 1355034-97-7.mol

Synonyms:C₂₇H₂₈FN₃O₉S

Chemical Property of C₂₇H₂₈FN₃O₉S

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₂₇H₂₈FN₃O₉S

There total 10 articles about C₂₇H₂₈FN₃O₉S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C11H8FN3S (1355034-72-8) + 4,5,6,8-tetra-O-acetyl-3,7-anhydro-1,1,2,2-tetradehydro-1,2-dideoxy-D-glycero-D-gulo-octitol (168105-32-6) → C27H28FN3O9S (1355034-97-7)

Guidance literature:

With copper(II) sulfate; sodium L-ascorbate; In dichloromethane; water; at 20 ℃;

DOI:10.1016/j.bmcl.2011.10.062

Reference yield:

5-(4-fluorophenyl)thiophene-2-carboxaldehyde (249504-38-9) → C27H28FN3O9S (1355034-97-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium tetrahydroborate / methanol / 0.33 h / -15 °C

2: diphenylphosphoranyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 0 - 20 °C

3: copper(II) sulfate; sodium L-ascorbate / dichloromethane; water / 20 °C

With sodium tetrahydroborate; diphenylphosphoranyl azide; copper(II) sulfate; 1,8-diazabicyclo[5.4.0]undec-7-ene; sodium L-ascorbate; In methanol; dichloromethane; water; toluene;

DOI:10.1016/j.bmcl.2011.10.062

Reference yield:

5-bromo-2-thiophencarboxaldehyde (4701-17-1) → C27H28FN3O9S (1355034-97-7)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrabutylammomium bromide; palladium diacetate; potassium carbonate / water / 3 h

2: sodium tetrahydroborate / methanol / 0.33 h / -15 °C

3: diphenylphosphoranyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 0 - 20 °C

4: copper(II) sulfate; sodium L-ascorbate / dichloromethane; water / 20 °C

With sodium tetrahydroborate; diphenylphosphoranyl azide; tetrabutylammomium bromide; palladium diacetate; potassium carbonate; copper(II) sulfate; 1,8-diazabicyclo[5.4.0]undec-7-ene; sodium L-ascorbate; In methanol; dichloromethane; water; toluene;

DOI:10.1016/j.bmcl.2011.10.062

upstream raw materials:

5-(4-fluorophenyl)thiophene-2-carboxaldehyde

5-bromo-2-thiophencarboxaldehyde

[5-(4-fluorophenyl)thiophen-2-yl]methanol

(3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl)tetrahydro-2H-pyran-2-one

Downstream raw materials:

C₁₉H₂₀FN₃O₅S