5-Oxazolidineaceticacid,4-ethoxy-3-methyl-2-oxo-,methylester(9CI)

Base Information

• Chemical Name: 5-Oxazolidineaceticacid,4-ethoxy-3-methyl-2-oxo-,methylester(9CI)
• CAS No.: 110991-58-7
• Molecular Formula: C₉H₁₅NO₅
• Molecular Weight: 217.222
• Mol file: 110991-58-7.mol

Synonyms:5-Oxazolidineaceticacid,4-ethoxy-3-methyl-2-oxo-,methylester(9CI)

Chemical Property of 5-Oxazolidineaceticacid,4-ethoxy-3-methyl-2-oxo-,methylester(9CI)

Chemical Property:

• Boiling Point: 356.3±27.0 °C(Predicted)
• PKA: -3.97±0.60(Predicted)
• PSA: 65.07000
• Density: 1.20±0.1 g/cm3(Predicted)
• LogP: 0.30060

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Oxazolidineaceticacid,4-ethoxy-3-methyl-2-oxo-,methylester(9CI)

There total 2 articles about 5-Oxazolidineaceticacid,4-ethoxy-3-methyl-2-oxo-,methylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

ethanol (64-17-5) + ((S)-4-Hydroxy-3-methyl-2-oxo-oxazolidin-5-yl)-acetic acid methyl ester (110991-50-9) → ((S)-4-Ethoxy-3-methyl-2-oxo-oxazolidin-5-yl)-acetic acid methyl ester (110991-58-7)

Guidance literature:

at 0 ℃; for 3h; pH 2.0;

DOI:10.3987/R-1987-02-0373

Reference yield:

((S)-3-Methyl-2,4-dioxo-oxazolidin-5-yl)-acetic acid methyl ester (110991-42-9) → ((S)-4-Ethoxy-3-methyl-2-oxo-oxazolidin-5-yl)-acetic acid methyl ester (110991-58-7)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄ / methanol / -20 °C

2: 50 percent / 3 h / 0 °C / pH 2.0

With sodium tetrahydroborate; In methanol;

DOI:10.3987/R-1987-02-0373

upstream raw materials:

ethanol

((S)-4-Hydroxy-3-methyl-2-oxo-oxazolidin-5-yl)-acetic acid methyl ester

((S)-3-Methyl-2,4-dioxo-oxazolidin-5-yl)-acetic acid methyl ester