Technology Process of ethyl 12-(3-chloro-5-formyl-2,6-dihydroxy-4-methylphenyl)dodecanoate
There total 6 articles about ethyl 12-(3-chloro-5-formyl-2,6-dihydroxy-4-methylphenyl)dodecanoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium on activated charcoal; hydrogen;
In
ethyl acetate;
at 0 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: oxalyl dichloride; dimethyl sulfoxide / chloroform / 3 h / -55 °C / Inert atmosphere
1.2: 0.75 h / -55 - 0 °C
2.1: calcium(II) chloride dihydrate; potassium hydroxide / methanol / 0.08 h / 0 °C
2.2: 16 h / 0 - 20 °C
3.1: phosphoric acid; acetic acid / 6 h / 70 °C
4.1: palladium on activated charcoal; hydrogen / ethyl acetate / 2 h / 0 °C
With
oxalyl dichloride; calcium(II) chloride dihydrate; phosphoric acid; palladium on activated charcoal; hydrogen; acetic acid; dimethyl sulfoxide; potassium hydroxide;
In
methanol; chloroform; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: calcium(II) chloride dihydrate; potassium hydroxide / methanol / 0.08 h / 0 °C
1.2: 16 h / 0 - 20 °C
2.1: phosphoric acid; acetic acid / 6 h / 70 °C
3.1: palladium on activated charcoal; hydrogen / ethyl acetate / 2 h / 0 °C
With
calcium(II) chloride dihydrate; phosphoric acid; palladium on activated charcoal; hydrogen; acetic acid; potassium hydroxide;
In
methanol; ethyl acetate;
