(2S)-2,3-dihydro-1H-indole-2-carboxamide

Base Information

Chemical Name:(2S)-2,3-dihydro-1H-indole-2-carboxamide
CAS No.:110660-78-1
Molecular Formula:C₉H₁₀N₂O
Molecular Weight:162.191
Hs Code.:
European Community (EC) Number:839-090-9
Mol file:110660-78-1.mol

Synonyms:(2S)-2,3-dihydro-1H-indole-2-carboxamide;110660-78-1;(S)-indoline-2-carboxamide;1H-Indole-2-carboxamide,2,3-dihydro-,(2S)-(9CI);SCHEMBL10742930;MFCD11982945;AKOS005622592;VS-02848;EN300-60029;G43184;Z760046840

Suppliers and Price of (2S)-2,3-dihydro-1H-indole-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2S)-2,3-Dihydro-1H-indole-2-carboxamide
50mg
$ 90.00

TRC
(2S)-2,3-Dihydro-1H-indole-2-carboxamide
5mg
$ 45.00

American Custom Chemicals Corporation
(2S)-2,3-DIHYDRO-1H-INDOLE-2-CARBOXAMIDE 95.00%
5G
$ 1295.03

American Custom Chemicals Corporation
(2S)-2,3-DIHYDRO-1H-INDOLE-2-CARBOXAMIDE 95.00%
2.5G
$ 1065.66

American Custom Chemicals Corporation
(2S)-2,3-DIHYDRO-1H-INDOLE-2-CARBOXAMIDE 95.00%
1G
$ 353.85

AK Scientific
(2S)-2,3-Dihydro-1H-indole-2-carboxamide
500mg
$ 289.00

AK Scientific
(2S)-2,3-Dihydro-1H-indole-2-carboxamide
100mg
$ 172.00

Total 2 raw suppliers

Chemical Property of (2S)-2,3-dihydro-1H-indole-2-carboxamide

Chemical Property:

Boiling Point:425.5±35.0 °C(Predicted)
PKA:15.38±0.20(Predicted)
PSA：55.12000
Density:1.219±0.06 g/cm3(Predicted)
LogP:1.34680
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:162.079312947
Heavy Atom Count:12
Complexity:193

Purity/Quality:

97% ^*data from raw suppliers

(2S)-2,3-Dihydro-1H-indole-2-carboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(NC2=CC=CC=C21)C(=O)N
Isomeric SMILES:C1[C@H](NC2=CC=CC=C21)C(=O)N

Technology Process of (2S)-2,3-dihydro-1H-indole-2-carboxamide

There total 3 articles about (2S)-2,3-dihydro-1H-indole-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 141410-06-2
(S)-indoline-2-carboxylic acid methyl ester

: 110660-78-1
(S)-2,3-dihydro-1H-indole-2-carboxamide

Guidance literature:: With ammonia; In methanol; at 20 ℃;
DOI:10.1021/jm0202831

Reference yield:

: 82923-81-7
(S)-2,3-dihydro-1H-indole-2-carboxylic acid ethyl ester

: 110660-78-1
(S)-2,3-dihydro-1H-indole-2-carboxamide

Guidance literature:: In methanol;

Reference yield:

: 79815-20-6,78348-24-0
(S)-indoline-2-carboxylic acid

: 110660-78-1
(S)-2,3-dihydro-1H-indole-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂

2: 91 percent / NH₃ / methanol / 20 °C

With thionyl chloride; ammonia; In methanol;
DOI:10.1021/jm0202831