2,4:3,5-dimethylene-D-mannitol 1-trans-cinnamate 6-(β-2-trans-thienylacrylate)

Base Information

• Chemical Name: 2,4:3,5-dimethylene-D-mannitol 1-trans-cinnamate 6-(β-2-trans-thienylacrylate)
• CAS No.: 73186-07-9
• Molecular Formula: C₂₄H₂₄O₈S
• Molecular Weight: 472.516
• Mol file: 73186-07-9.mol

Synonyms:2,4:3,5-dimethylene-D-mannitol 1-trans-cinnamate 6-(β-2-trans-thienylacrylate)

Chemical Property of 2,4:3,5-dimethylene-D-mannitol 1-trans-cinnamate 6-(β-2-trans-thienylacrylate)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4:3,5-dimethylene-D-mannitol 1-trans-cinnamate 6-(β-2-trans-thienylacrylate)

There total 3 articles about 2,4:3,5-dimethylene-D-mannitol 1-trans-cinnamate 6-(β-2-trans-thienylacrylate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Cinnamoyl chloride (102-92-1,17082-09-6) → 2,4:3,5-dimethylene-D-mannitol 1-trans-cinnamate 6-(β-2-trans-thienylacrylate) (73186-07-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.77 g / pyridine / benzene / 40 h / Ambient temperature

2: 0.76 g / pyridine / benzene / in the cold, 2 h, room temperature 20 h

With pyridine; In benzene;

DOI:10.1021/ja00521a051

Reference yield:

2,4:3,5-di-O-methylene-D-mannitol (73209-88-8) → 2,4:3,5-dimethylene-D-mannitol 1-trans-cinnamate 6-(β-2-trans-thienylacrylate) (73186-07-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.77 g / pyridine / benzene / 40 h / Ambient temperature

2: 0.76 g / pyridine / benzene / in the cold, 2 h, room temperature 20 h

With pyridine; In benzene;

DOI:10.1021/ja00521a051

Reference yield:

(2E)-3-(2-thiophenyl)-2-propenoyl chloride (28424-61-5,73186-06-8,119924-24-2) + 2,4:3,5-dimethylene-D-mannitol 1-trans-cinnamate (73186-05-7) → 2,4:3,5-dimethylene-D-mannitol 1-trans-cinnamate 6-(β-2-trans-thienylacrylate) (73186-07-9)

Guidance literature:

With pyridine; In benzene; in the cold, 2 h, room temperature 20 h;

DOI:10.1021/ja00521a051

upstream raw materials:

(2E)-3-(2-thiophenyl)-2-propenoyl chloride

2,4:3,5-dimethylene-D-mannitol 1-trans-cinnamate

Cinnamoyl chloride

2,4:3,5-di-O-methylene-D-mannitol