2'-Bromo-2'-deoxy-5-methyluridine 3',5'-diacetate

Base Information

Chemical Name:2'-Bromo-2'-deoxy-5-methyluridine 3',5'-diacetate
CAS No.:110483-43-7
Molecular Formula:C14H17 Br N2 O7
Molecular Weight:405.202
Hs Code.:
European Community (EC) Number:600-967-4
DSSTox Substance ID:DTXSID40911707
Mol file:110483-43-7.mol

Synonyms:110483-43-7;2'-Bromo-2'-deoxy-5-methyluridine 3',5'-diacetate;((2R,3R,4R,5R)-3-Acetoxy-4-bromo-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methylacetate;[(2R,3R,4R,5R)-3-acetyloxy-4-bromo-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate;SCHEMBL8424714;DTXSID40911707;AKOS027327922;3',5'-Di-O-acetyl-2'-bromothymidine;F12847

Suppliers and Price of 2'-Bromo-2'-deoxy-5-methyluridine 3',5'-diacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2'-Bromo-2'-deoxy-5-methyluridine 3',5'-diacetate

Chemical Property:

PKA:9.55±0.10(Predicted)
PSA：116.69000
Density:1.61±0.1 g/cm3(Predicted)
LogP:0.00070
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:404.02191
Heavy Atom Count:24
Complexity:606

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COC(=O)C)OC(=O)C)Br
Isomeric SMILES:CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COC(=O)C)OC(=O)C)Br

Technology Process of 2'-Bromo-2'-deoxy-5-methyluridine 3',5'-diacetate

There total 1 articles about 2'-Bromo-2'-deoxy-5-methyluridine 3',5'-diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 506-96-7
Acetyl bromide

: 2',3'-O-methoxyethylidene-5-methyluridine

: 110483-43-7
1-(3,5-di-O-acetyl-2-bromo-2-deoxy-β-D-ribofuranosyl)thymine

: 65-71-4,28806-14-6,691841-57-3
thymin

: 4336-39-4,4645-02-7
(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate

: 1-(3-O-acetyl-2,5-dibromo-2,5-dideoxy-β-D-ribofuranosyl)thymine

Guidance literature:: With hydrogen bromide; acetic acid; In acetonitrile; at 50 - 60 ℃; for 5h; Yield given. Yields of byproduct given;
DOI:10.1080/07328319608002369