diphenyl 7-phosphate

Base Information

• Chemical Name: diphenyl 7-phosphate
• CAS No.: 90318-58-4
• Molecular Formula: C₂₁H₂₅O₁₀P
• Molecular Weight: 468.397
• Mol file: 90318-58-4.mol

Synonyms:diphenyl 7-phosphate

Chemical Property of diphenyl 7-phosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diphenyl 7-phosphate

There total 4 articles about diphenyl 7-phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl (methyl 3-deoxy-α-D-arabino-2-heptulopyranosid)onate (2880-95-7,85549-51-5) + chlorophosphoric acid diphenyl ester (2524-64-3) → diphenyl 7-phosphate (90318-58-4,91382-79-5)

Guidance literature:

In pyridine; at -20 ℃; for 0.5h;

DOI:10.1016/S0008-6215(96)00227-3

Reference yield: 84.0%

methyl (methyl 3-deoxy-α-D-arabino-2-heptulopyranosid)onate (2880-95-7,85549-51-5) + Diphenylphosphinic chloride (1499-21-4) → diphenyl 7-phosphate (90318-58-4,91382-79-5)

Guidance literature:

In pyridine; benzene; -10 deg.C to room temp;

DOI:10.1016/0008-6215(84)85101-0

Reference yield:

(2R,4R,5S,6R)-4,5-Diacetoxy-6-acetoxymethyl-2-methoxy-tetrahydro-pyran-2-carboxylic acid methyl ester (85464-51-3) → diphenyl 7-phosphate (90318-58-4,91382-79-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / NaHCO₃ / methanol / 1 h / Ambient temperature

2: 95 percent / pyridine / 0.5 h / -20 °C

With sodium hydrogencarbonate; In pyridine; methanol;

DOI:10.1016/S0008-6215(96)00227-3

upstream raw materials:

methyl (methyl 3-deoxy-α-D-arabino-2-heptulopyranosid)onate

Diphenylphosphinic chloride

chlorophosphoric acid diphenyl ester

(2R,4R,5S,6R)-4,5-Diacetoxy-6-acetoxymethyl-2-methoxy-tetrahydro-pyran-2-carboxylic acid methyl ester

Downstream raw materials:

(methyl 3-deoxy-D-arabino-2-heptulopyranosid)onic acid dihydrogen 7-phosphate

methyl (methyl 3-deoxy-α-D-arabino-hept-2-ulopyranosid)onate 7-(dihydrogen phosphate)