Chemical Property of Diphenyl chlorophosphate
Chemical Property:
- Appearance/Colour:clear colourless to light yellow liquid
- Vapor Pressure:10 mm Hg ( 190 °C)
- Melting Point:314-316oC
- Refractive Index:n20/D 1.55(lit.)
- Boiling Point:363.5 °C at 760 mmHg
- Flash Point:256.2 °C
- PSA：45.34000
- Density:1.337 g/cm3
- LogP:4.49130
- Storage Temp.:Store below +30°C.
- Sensitive.:Moisture Sensitive
- Water Solubility.:MAY DECOMPOSE
- XLogP3:3.5
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:4
- Exact Mass:268.0056089
- Heavy Atom Count:17
- Complexity:249
- Transport DOT Label:Corrosive
- Purity/Quality:
-
99% *data from raw suppliers
DiphenylChlorophosphonate *data from reagent suppliers
Safty Information:
- Pictogram(s):
C
- Hazard Codes:C
- Statements:
34-37
- Safety Statements:
26-36/37/39-45-7-24/25-23
- MSDS Files:
-
SDS file from LookChem
Total 1 MSDS from other Authors
Useful:
- Canonical SMILES:C1=CC=C(C=C1)OP(=O)(OC2=CC=CC=C2)Cl
-
Description
Diphenyl chlorophosphate is a viscous colorless liquid. It can be prepared in situ by the reaction between diphenyl hydrogen phosphonate and carbon tetrachloride. It is used to prepare aromatic polyesters by polycondensation reaction in pyridine and polyesteramide. Diphenyl chlorophosphate is used as a phosphonating agent, such as to prepare phenylphosphonic acid.
-
Uses
Diphenyl chlorophosphate can be used to synthesize methadone, an opioid used for opioid maintenance therapy and for pain relief. It is used to control seedling grasses in turf. It undergoes anhydrous condensation with ethyl-4-bromo-butyrate and the hydrolysis product in alkaline medium of this condensation reaction is used in the quantitative determination of 3-cyano-3,3-diphenylpropionic acid. Diphenyl chlorophosphate?is used to prepare cyclohexyl-amidophosphoric acid diphenyl ester by reacting with cyclohexylamine. It is also used in the synthesis of alfa-substituted beta-lactams, anhydrides, esters and thioesters. It is also employed in the conversion of aldoximes to nitriles. Further, it is used in the preparation and reaction of enol phosphates, guanosine-adenosine-5',5'-triphosphate, guanosine-cytidine-5',5'-triphosphate, guanosine-uridine-5',5'-triphosphate, diguanosine-5',5'-diphosphate and diguanosine-5',5'-triphosphate. In addition to this, it serves as a phosphorylating agent for the preparation of 2-deoxy-D-galactose-3 and -6 phosphoric acids. Diphenyl chlorophosphate may be used:in the preparation of guanosine-adenosine-5′,5′-triphosphate, guanosine-cytidine-5′,5′-triphosphate, guanosine-uridine-5′,5′-triphosphate, diguanosine-5′,5′-diphosphate and diguanosine-5′,5′-triphosphateas phosphorylating agent for the synthesis of 2-deoxy-D-galactose-3 and -6 phosphoric acidsin the synthesis of diaryl phosphoryl derivatives of alkylene dithiophosphates
