Methyl (2-(hydroxymethyl)phenyl)carbamate

Base Information

Chemical Name:Methyl (2-(hydroxymethyl)phenyl)carbamate
CAS No.:117550-36-4
Molecular Formula:C₉H₁₁NO₃
Molecular Weight:181.191
Hs Code.:
DSSTox Substance ID:DTXSID001044603

Synonyms:117550-36-4;Methyl (2-(hydroxymethyl)phenyl)carbamate;methyl N-[2-(hydroxymethyl)phenyl]carbamate;Carbamic acid, [2-(hydroxymethyl)phenyl]-, methyl ester;SCHEMBL2462870;QNCPWLXCDKFGEK-UHFFFAOYSA-N;DTXSID001044603;MFCD14680132;AKOS010759206;Methyl(2-(hydroxymethyl)phenyl)carbamate;AS-69944;CS-0038874;W11200;(2-Hydroxymethyl-phenyl)carbamic acid methyl ester;(2-Hydroxymethyl-phenyl)-carbamic acid methyl ester

Suppliers and Price of Methyl (2-(hydroxymethyl)phenyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of Methyl (2-(hydroxymethyl)phenyl)carbamate

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:181.07389321
Heavy Atom Count:13
Complexity:172

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)NC1=CC=CC=C1CO

Technology Process of Methyl (2-(hydroxymethyl)phenyl)carbamate

There total 2 articles about Methyl (2-(hydroxymethyl)phenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 5344-90-1
2-Aminobenzyl alcohol

: 79-22-1
methyl chloroformate

: 117550-36-4
methyl ortho-(hydroxymethyl)phenyl carbamate

Guidance literature:: With sodium hydrogencarbonate; In 1,4-dioxane; water;
DOI:10.1021/jo981816+

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 117550-36-4
methyl ortho-(hydroxymethyl)phenyl carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere

2: sodium hydrogencarbonate / 1,4-dioxane; water / 2 h / 0 - 20 °C / Inert atmosphere

With lithium aluminium tetrahydride; sodium hydrogencarbonate; In tetrahydrofuran; 1,4-dioxane; water;
DOI:10.1021/acs.orglett.8b00905