2-(Quinolin-4-YL)acetic acid

Base Information

Chemical Name:2-(Quinolin-4-YL)acetic acid
CAS No.:109922-57-8
Molecular Formula:C11H9 N O2
Molecular Weight:187.198
Hs Code.:2933499090
DSSTox Substance ID:DTXSID30590626
Wikidata:Q72505793
Mol file:109922-57-8.mol

Synonyms:109922-57-8;2-(QUINOLIN-4-YL)ACETIC ACID;4-Quinolineacetic acid;2-quinolin-4-ylacetic acid;Quinoline-4-aceticacid;Quinoline-4-acetic acid;(Quinolin-4-yl)acetic acid;4-Chinolyl-essig;SCHEMBL5456634;DTXSID30590626;AKOS006278537;SB68234;DA-38975;CS-0451071;EN300-315479;F94796;W-204726

Suppliers and Price of 2-(Quinolin-4-YL)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
2-(quinolin-4-yl)acetic acid 95
10g
$ 2292.00

Labseeker
2-(quinolin-4-yl)acetic acid 95
5g
$ 1633.00

Labseeker
2-(quinolin-4-yl)acetic acid 95
1g
$ 1333.00

Crysdot
2-(Quinolin-4-yl)aceticacid 97%
1g
$ 620.00

Chemenu
2-(quinolin-4-yl)aceticacid 97%
1g
$ 580.00

American Custom Chemicals Corporation
2-(QUINOLIN-4-YL)ACETIC ACID 95.00%
5G
$ 1756.06

Alichem
Quinoline-4-aceticacid
1g
$ 937.41

Total 14 raw suppliers

Chemical Property of 2-(Quinolin-4-YL)acetic acid

Chemical Property:

Vapor Pressure:6.34E-07mmHg at 25°C
Refractive Index:1.66
Boiling Point:394.3°C at 760 mmHg
PKA:2.92±0.30(Predicted)
Flash Point:192.3°C
PSA：50.19000
Density:1.297g/cm³
LogP:1.86190
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:187.063328530
Heavy Atom Count:14
Complexity:217

Purity/Quality:

97% ^*data from raw suppliers

2-(quinolin-4-yl)acetic acid 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CC=N2)CC(=O)O

Technology Process of 2-(Quinolin-4-YL)acetic acid

There total 2 articles about 2-(Quinolin-4-YL)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 491-35-0
C₆H₄NCH₂CHCCH₂

: 124-38-9,18923-20-1
carbon dioxide

: 109922-57-8
[4]quinolyl-acetic acid

Guidance literature:: With pyridine hydrochloride; lithium diisopropyl amide; Multistep reaction;
DOI:10.1016/S0040-4039(00)85384-8

Reference yield:

: 4789-81-5
ethyl 4-quinolineacetate

: 109922-57-8
[4]quinolyl-acetic acid

Guidance literature:: With sodium hydroxide;

Reference yield:

: 109922-57-8
[4]quinolyl-acetic acid

: 485-64-3
(-)-hydrocinchonidine

Guidance literature:: Multi-step reaction with 5 steps

1: 90 percent / pyridine hydrochloride / methanol; pyridine; various solvent(s) / 36 h / Ambient temperature

2: 1) water 2.) NH4OAc, NaCNBH3 / 1) β-glucosidase / 2.) pH=6.2, 18 h

3: 1.) 3percent HCl, 2.) NaCNBH₃ / 1.) aq MeOH, reflux, 40 min

4: 2.) CF₃CO₃H, Na₂HPO₄ / 1.) 0 grad C, 2.) CH₂Cl₂, rt, 12 h

5: 1.) K₂CO₃ / 1.) MeOH, rt, 2 h, 2.) toluene, EtOH, reflux 24 h

With hydrogenchloride; disodium hydrogenphosphate; trifluoroacetyl peroxide; ammonium acetate; water; pyridine hydrochloride; sodium cyanoborohydride; potassium carbonate; β-glucosidase; In pyridine; methanol;
DOI:10.1016/S0040-4039(00)85384-8