(S)-3-(3,4-Dimethoxybenzyloxy)propane-1,2-diyl Dioleate

Base Information

• Chemical Name: (S)-3-(3,4-Dimethoxybenzyloxy)propane-1,2-diyl Dioleate
• CAS No.: 139115-88-1
• Molecular Formula: C₄₈H₈₂O₇
• Molecular Weight: 771.175
• Mol file: 139115-88-1.mol

Synonyms:(S)-3-(3,4-Dimethoxybenzyloxy)propane-1,2-diyl Dioleate

Chemical Property of (S)-3-(3,4-Dimethoxybenzyloxy)propane-1,2-diyl Dioleate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (S)-3-(3,4-Dimethoxybenzyloxy)propane-1,2-diyl Dioleate

There total 3 articles about (S)-3-(3,4-Dimethoxybenzyloxy)propane-1,2-diyl Dioleate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

(Z)-9-octadecenoyl chloride (112-77-6) + 2(R)-3-((3,4-dimethoxybenzyl)oxy)propane-1,2-diol (139115-87-0) → (S)-3-(3,4-Dimethoxybenzyloxy)propane-1,2-diyl Dioleate (139115-88-1)

Guidance literature:

With pyridine; In dichloromethane; Heating;

DOI:10.1002/hlca.19910740810

Reference yield:

(S)-4-<(3,4-Dimethoxybenzyloxy)methyl>-2,2-dimethyl-1,3-dioxolane (139115-86-9) → (S)-3-(3,4-Dimethoxybenzyloxy)propane-1,2-diyl Dioleate (139115-88-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / 10percent aq. acetic acid / 2 h / 70 - 80 °C

2: 94 percent / pyridine / CH₂Cl₂ / Heating

With pyridine; acetic acid; In dichloromethane;

DOI:10.1002/hlca.19910740810

Reference yield:

4-chloromethyl-1,2-dimethoxy-benzene (7306-46-9) → (S)-3-(3,4-Dimethoxybenzyloxy)propane-1,2-diyl Dioleate (139115-88-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 1) NaH, hexamethylphosphoric triamide (HMPA) / 1) THF, 0 deg C, 10 min, 2) reflux, 12 h

2: 94 percent / 10percent aq. acetic acid / 2 h / 70 - 80 °C

3: 94 percent / pyridine / CH₂Cl₂ / Heating

With pyridine; N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydride; acetic acid; In dichloromethane;

DOI:10.1002/hlca.19910740810

upstream raw materials:

(Z)-9-octadecenoyl chloride

2(R)-3-((3,4-dimethoxybenzyl)oxy)propane-1,2-diol

(S)-4-<(3,4-Dimethoxybenzyloxy)methyl>-2,2-dimethyl-1,3-dioxolane

4-chloromethyl-1,2-dimethoxy-benzene

Downstream raw materials:

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine