2-(3,5-difluorophenyl)acetaldehyde

Base Information

• Chemical Name: 2-(3,5-difluorophenyl)acetaldehyde
• CAS No.: 109346-94-3
• Molecular Formula: C8H6 F2 O
• Molecular Weight: 156.132
• Hs Code.: 2913000090
• Mol file: 109346-94-3.mol

Synonyms:2-(3,5-Difluorophenyl)acetaldehyde

Chemical Property of 2-(3,5-difluorophenyl)acetaldehyde

Chemical Property:

• PSA: 17.07000
• LogP: 1.70620

Purity/Quality:

98.5% ^*data from raw suppliers

3,5-Difluorobenzeneacetaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(3,5-difluorophenyl)acetaldehyde

There total 3 articles about 2-(3,5-difluorophenyl)acetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-(3,5-difluorophenyl)ethan-1-ol (467223-90-1) → 2-(3,5-difluorophenyl)acetaldehyde (109346-94-3)

Guidance literature:

With Dess-Martin periodane; In dichloromethane;

Reference yield: 85.4%

1,3-difluoro-5-(2-methoxyethenyl)benzene → 2-(3,5-difluorophenyl)acetaldehyde (109346-94-3)

Guidance literature:

With hydrogenchloride; In toluene; for 6h;

Reference yield:

methyl 2-(3,5-difluorophenyl)acetate (210530-70-4) → 2-(3,5-difluorophenyl)acetaldehyde (109346-94-3)

Guidance literature:

methyl 2-(3,5-difluorophenyl)acetate; With diisobutylaluminium hydride; In dichloromethane; at -78 ℃; for 1h;

With methanol; In dichloromethane; at -78 ℃;

upstream raw materials:

methyl 2-(3,5-difluorophenyl)acetate

2-(3,5-difluorophenyl)ethan-1-ol

Downstream raw materials:

C₁₀H₁₀F₂O

C₂₄H₃₅F₂N₅O

Refernces

• 1、 -. "Phosphinic acids". Page/Page column 8. . Retrieved 2010/02/11.