N-(cyclopropylmethyl)-7-{2,6-dimethoxy-4-[(tetrahydro-2H-pyran-2-yloxy)methyl]phenyl}-2-ethyl-N-(tetrahydro-2H-pyran-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine

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Chemical Name:N-(cyclopropylmethyl)-7-{2,6-dimethoxy-4-[(tetrahydro-2H-pyran-2-yloxy)methyl]phenyl}-2-ethyl-N-(tetrahydro-2H-pyran-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine
CAS No.:1144100-29-7
Molecular Formula:C₃₃H₄₅N₃O₅
Molecular Weight:563.737
Hs Code.:

N-(cyclopropylmethyl)-7-{2,6-dimethoxy-4-[(tetrahydro-2H-pyran-2-yloxy)methyl]phenyl}-2-ethyl-N-(tetrahydro-2H-pyran-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine

Synonyms:N-(cyclopropylmethyl)-7-{2,6-dimethoxy-4-[(tetrahydro-2H-pyran-2-yloxy)methyl]phenyl}-2-ethyl-N-(tetrahydro-2H-pyran-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine

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Chemical Property of N-(cyclopropylmethyl)-7-{2,6-dimethoxy-4-[(tetrahydro-2H-pyran-2-yloxy)methyl]phenyl}-2-ethyl-N-(tetrahydro-2H-pyran-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine

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Technology Process of N-(cyclopropylmethyl)-7-{2,6-dimethoxy-4-[(tetrahydro-2H-pyran-2-yloxy)methyl]phenyl}-2-ethyl-N-(tetrahydro-2H-pyran-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine

There total 1 articles about N-(cyclopropylmethyl)-7-{2,6-dimethoxy-4-[(tetrahydro-2H-pyran-2-yloxy)methyl]phenyl}-2-ethyl-N-(tetrahydro-2H-pyran-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: N-cyclopropylmethyl-N-(2-ethyl-7-iodopyrazolo[1,5-a]pyridine-3-yl)-N-(tetrahydro-2H-pyran-4-ylmethyl)amine hydrochloride

: {2,6-dimethoxy-4-[(tetrahydro-2H-pyran-2-yloxy)methyl]phenyl}boronic acid

: 1144100-29-7
N-(cyclopropylmethyl)-7-{2,6-dimethoxy-4-[(tetrahydro-2H-pyran-2-yloxy)methyl]phenyl}-2-ethyl-N-(tetrahydro-2H-pyran-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine

Guidance literature:: With potassium carbonate; palladium diacetate; triphenylphosphine; In 1,2-dimethoxyethane; water; at 95 ℃; for 6h;

Reference yield: 82.8%

: 1144100-29-7
N-(cyclopropylmethyl)-7-{2,6-dimethoxy-4-[(tetrahydro-2H-pyran-2-yloxy)methyl]phenyl}-2-ethyl-N-(tetrahydro-2H-pyran-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine

: 685885-79-4
[4-(3-{(cyclopropylmethyl)[(tetrahydro-2H-pyran-4-yl)-methyl]amino}-2-ethylpyrazolo[1,5-a]pyridin-7-yl)-3,5-dimethoxyphenyl]methanol

Guidance literature:: N-(cyclopropylmethyl)-7-{2,6-dimethoxy-4-[(tetrahydro-2H-pyran-2-yloxy)methyl]phenyl}-2-ethyl-N-(tetrahydro-2H-pyran-4-ylmethyl)pyrazolo[1,5-a]pyridin-3-amine; With hydrogenchloride; In water; toluene; at 20 ℃; for 3h;

With sodium hydroxide; In water; ethyl acetate; pH=13;

With sodium hydroxide; Product distribution / selectivity;