Quinoxaline, 1,2,3,4-tetrahydro-2,4-dimethyl-1-nitroso- (9CI)

Base Information

• Chemical Name: Quinoxaline, 1,2,3,4-tetrahydro-2,4-dimethyl-1-nitroso- (9CI)
• CAS No.: 109055-64-3
• Molecular Formula: C₁₀H₁₃N₃O
• Molecular Weight: 191.233
• Hs Code.: 2933990090
• Mol file: 109055-64-3.mol

Synonyms:Quinoxaline, 1,2,3,4-tetrahydro-2,4-dimethyl-1-nitroso- (9CI);2,4-DIMETHYL-1-NITROSO-1,2,3,4-TETRAHYDROQUINOXALINE

Chemical Property of Quinoxaline, 1,2,3,4-tetrahydro-2,4-dimethyl-1-nitroso- (9CI)

Chemical Property:

• PSA: 35.91000
• LogP: 2.14270

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Quinoxaline, 1,2,3,4-tetrahydro-2,4-dimethyl-1-nitroso- (9CI)

There total 4 articles about Quinoxaline, 1,2,3,4-tetrahydro-2,4-dimethyl-1-nitroso- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

1-nitroso-2-metil-1,2,3,4-tetraidrochinossalina (109055-60-9) + methyl iodide (74-88-4) → 1-nitroso-2,4-dimetil-1,2,3,4-tetraidrochinossalina (109055-64-3)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; for 2h; Ambient temperature;

Reference yield:

2-methyl-1,2,3,4-tetrahydroquinoxaline (6640-55-7,24463-30-7,24463-31-8,49849-47-0) → 1-nitroso-2,4-dimetil-1,2,3,4-tetraidrochinossalina (109055-64-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) triethylamine, 2.) HCl / 1.) ethanol, 90 min, room temp., 2.) ethanol

2: 91.1 percent / sodium nitrite, 2N HCl / H₂O / first 0 deg C then room temperature, 2 h

3: 67.8 percent / 2N NaOH / ethanol / 2 h / Heating

4: 55 percent / KOH powder / dimethylsulfoxide / 2 h / Ambient temperature

With hydrogenchloride; potassium hydroxide; sodium hydroxide; triethylamine; sodium nitrite; In ethanol; water; dimethyl sulfoxide;

Reference yield:

1-nitroso-2-metil-4-carbetossi-1,2,3,4-tetraidrochinossalina (109055-63-2) → 1-nitroso-2,4-dimetil-1,2,3,4-tetraidrochinossalina (109055-64-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 67.8 percent / 2N NaOH / ethanol / 2 h / Heating

2: 55 percent / KOH powder / dimethylsulfoxide / 2 h / Ambient temperature

With potassium hydroxide; sodium hydroxide; In ethanol; dimethyl sulfoxide;

upstream raw materials:

1-nitroso-2-metil-1,2,3,4-tetraidrochinossalina

methyl iodide

2-methyl-1,2,3,4-tetrahydroquinoxaline

1-nitroso-2-metil-4-carbetossi-1,2,3,4-tetraidrochinossalina