N-tert-butyloxycarbonyl-O-tert-butyloxycarbonyl-L-tyrosyl-glygylglicine

Base Information

• Chemical Name: N-tert-butyloxycarbonyl-O-tert-butyloxycarbonyl-L-tyrosyl-glygylglicine
• CAS No.: 88829-53-2
• Molecular Formula: C₂₃H₃₃N₃O₉
• Molecular Weight: 495.53

Synonyms:N-tert-butyloxycarbonyl-O-tert-butyloxycarbonyl-L-tyrosyl-glygylglicine

Chemical Property of N-tert-butyloxycarbonyl-O-tert-butyloxycarbonyl-L-tyrosyl-glygylglicine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-tert-butyloxycarbonyl-O-tert-butyloxycarbonyl-L-tyrosyl-glygylglicine

There total 1 articles about N-tert-butyloxycarbonyl-O-tert-butyloxycarbonyl-L-tyrosyl-glygylglicine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

glycylglycine (556-50-3) + (S)-2-(tert-butoxycarbonylamino)-3-(4-(tert-butoxycarbonyloxy)phenyl)propanoic acid (20866-48-2) → N-tert-butyloxycarbonyl-O-tert-butyloxycarbonyl-L-tyrosyl-glygylglicine (88829-53-2) + 1,3-Dicyclohexylurea (2387-23-7)

Guidance literature:

With sodium hydroxide; 1-hydroxy-pyrrolidine-2,5-dione; sodium hydrogencarbonate; dicyclohexyl-carbodiimide; Yield given. Multistep reaction; 1) DNF, 0 deg C, 1 h, 2) DMF, RT, 2 h, 3) DMF, RT, 1 h;

DOI:10.1016/S0040-4020(01)89092-X

Reference yield: 92.0%

N-tert-butyloxycarbonyl-O-tert-butyloxycarbonyl-L-tyrosyl-glygylglicine (88829-53-2) + trifluoroacetic acid (76-05-1) → L-tyrosylglycylglycine trifluoroacetate salt

Guidance literature:

With methoxybenzene; at 20 ℃; for 0.5h;

DOI:10.1016/j.carres.2003.07.011

Reference yield: 69.0%

N-tert-butyloxycarbonyl-O-tert-butyloxycarbonyl-L-tyrosyl-glygylglicine (88829-53-2) + pentachlorophenol-dicyclohexylcarbodiimid complex (126369-89-9) → N-tert-butyloxycarbonyl-O-tert-butyloxycarbonyl-L-tyrosyl-glycylglycine pentachlorophenyl ester (126369-86-6)

Guidance literature:

In dichloromethane;

DOI:10.1016/S0040-4020(01)89092-X

upstream raw materials:

glycylglycine

(S)-2-(tert-butoxycarbonylamino)-3-(4-(tert-butoxycarbonyloxy)phenyl)propanoic acid

Downstream raw materials:

(S)-2-[(S)-2-(2-{2-[(S)-2-tert-Butoxycarbonylamino-3-(4-tert-butoxycarbonyloxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-thiopropionylamino]-4-methyl-pentanoic acid methyl ester

N-tert-butyloxycarbonyl-O-tert-butyloxycarbonyl-L-tyrosyl-glycylglycine pentachlorophenyl ester

2-{2-[2-(2-{2-[2-tert-butoxycarbonylamino-3-(4-tert-butoxycarbonyloxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyrylamino}-adamantane-2-carboxylic acid

3-({2-[2-(2-{2-[2-tert-butoxycarbonylamino-3-(4-tert-butoxycarbonyloxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyrylamino}-methyl)-adamantane-1-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 88829-53-2 N-tert-butyloxycarbonyl-O-tert-butyloxycarbonyl-L-tyrosyl-glygylglicine

Send

Send

Metric Ton KG G Pound L ML

Send

Send