Florfenicol Amine Hydrochloride

Base Information

Chemical Name:Florfenicol Amine Hydrochloride
CAS No.:108656-33-3
Molecular Formula:C₁₀H₁₄FNO₃S*ClH
Molecular Weight:283.751
Hs Code.:
European Community (EC) Number:976-101-7
Mol file:108656-33-3.mol

Synonyms:Florfenicol Amine Hydrochloride;108656-33-3;2-amino-3-fluoro-1-(4-methylsulfonylphenyl)propan-1-ol;hydrochloride;FLORFENICOL AMINE, HYDROCHLORIDE;Flufenicol impurities 3;SCHEMBL9177460;HWPBPTAOXVIKGI-UHFFFAOYSA-N;AKOS030255539;J-002175

Suppliers and Price of Florfenicol Amine Hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Florfenicol Amine, Hydrochloride
10mg
$ 425.00

TRC
FlorfenicolAmineHydrochloride
25mg
$ 370.00

TRC
FlorfenicolAmineHydrochloride
100mg
$ 1210.00

Medical Isotopes, Inc.
FlorfenicolAmineHCl
50 mg
$ 1880.00

Medical Isotopes, Inc.
FlorfenicolAmineHCl
10 mg
$ 860.00

Cayman Chemical
Florfenicol amine (hydrochloride) ≥95%
10mg
$ 210.00

Cayman Chemical
Florfenicol amine (hydrochloride) ≥95%
5mg
$ 56.00

Cayman Chemical
Florfenicol amine (hydrochloride) ≥95%
1mg
$ 35.00

Biorbyt Ltd
Florfenicol Amine Hydrochloride
50 μg
$ 425.00

Biorbyt Ltd
Florfenicol Amine Hydrochloride
500 μg
$ 957.10

Total 13 raw suppliers

Chemical Property of Florfenicol Amine Hydrochloride

Chemical Property:

Melting Point:162-164°C
PSA：88.77000
LogP:3.00340
Storage Temp.:-20°C Freezer
Solubility.:Methanol (Slightly, Sonicated), Water (Slightly)
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:283.0445204
Heavy Atom Count:17
Complexity:307

Purity/Quality:

99% ^*data from raw suppliers

Florfenicol Amine, Hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)C1=CC=C(C=C1)C(C(CF)N)O.Cl
Uses A Florfenicol intermediate as antibacterial agent. A Florfenicol (F405750) intermediate as antibacterial agent. Florfenicol AMine Hydrochloride is a major metabolite of the antibiotic florfenicol, a fluorinated derivative of chloramphenicol that is commonly used in veterinary medicine. The pharmacokinetics of florfenicol and florfenicol amine are commonly studied in edible tissues from domestic animals.[Cayman Chemical]

Technology Process of Florfenicol Amine Hydrochloride

There total 12 articles about Florfenicol Amine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: tert-butyl {(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}carbamate

: 108656-33-3
(1R,2S)-2-amino-3-fluoro-1-(4-methylsulphonylphenyl)-1-propanol hydrochloride

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 0 - 20 ℃; for 2h;
DOI:10.1002/ejoc.201800658

Reference yield: 68.0%

: tert-butyl {(4R,5R)-4-[4-(methylsulfonyl)phenyl]-2,2-dioxido-1,3,2-dioxathian-5-yl}carbamate

: 108656-33-3
(1R,2S)-2-amino-3-fluoro-1-(4-methylsulphonylphenyl)-1-propanol hydrochloride

Guidance literature:: tert-butyl {(4R,5R)-4-[4-(methylsulfonyl)phenyl]-2,2-dioxido-1,3,2-dioxathian-5-yl}carbamate; With triethylamine tris(hydrogen fluoride); In 1,2-dichloro-ethane; at 70 ℃; for 8h;

With hydrogenchloride; In ethyl acetate; at 0 - 20 ℃; for 2h;
DOI:10.1002/ejoc.201800658