1,2,3,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]-1-isoquinolineethanamine

Base Information

Chemical Name:1,2,3,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]-1-isoquinolineethanamine
CAS No.:222022-28-8
Molecular Formula:C₁₈H₂₂N₂O₂S
Molecular Weight:330.451
Hs Code.:

Synonyms:1,2,3,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]-1-isoquinolineethanamine

Suppliers and Price of 1,2,3,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]-1-isoquinolineethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,2,3,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]-1-isoquinolineethanamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,2,3,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]-1-isoquinolineethanamine

There total 9 articles about 1,2,3,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]-1-isoquinolineethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 222022-30-2
2-{2-[2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-1-yl]-ethyl}-isoindole-1,3-dione

: 222022-28-8
1,2,3,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]-1-isoquinolineethanamine

Guidance literature:: With hydrazine hydrate; In ethanol; for 18h; Heating;
DOI:10.1016/S0968-0896(01)00017-7

Reference yield:

: 64-04-0
phenethylamine

: 222022-28-8
1,2,3,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]-1-isoquinolineethanamine

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / pyridine / 18 h / 20 °C

2: 90 percent / CF₃COOH / 1.5 h / Heating

3: 97 percent / hydrazine monohydrate / ethanol / 18 h / Heating

With hydrazine hydrate; trifluoroacetic acid; In pyridine; ethanol; 2: Pictet-Spengler cyclization;
DOI:10.1016/S0968-0896(01)00017-7

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 222022-28-8
1,2,3,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]-1-isoquinolineethanamine

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / pyridine / 18 h / 20 °C

2: 90 percent / CF₃COOH / 1.5 h / Heating

3: 97 percent / hydrazine monohydrate / ethanol / 18 h / Heating

With hydrazine hydrate; trifluoroacetic acid; In pyridine; ethanol; 2: Pictet-Spengler cyclization;
DOI:10.1016/S0968-0896(01)00017-7