1,3-Diphenylpyrazole-4-propionic acid

Base Information

Chemical Name:1,3-Diphenylpyrazole-4-propionic acid
CAS No.:108446-77-1
Molecular Formula:C18H16 N2 O2
Molecular Weight:292.337
Hs Code.:2933199090
DSSTox Substance ID:DTXSID90546068
Wikidata:Q82423767
Mol file:108446-77-1.mol

Synonyms:108446-77-1;1,3-Diphenylpyrazole-4-propionic acid;3-(1,3-Diphenyl-1H-pyrazol-4-yl)propanoic acid;3-(1,3-DIPHENYLPYRAZOL-4-YL)PROPANOIC ACID;Oprea1_716783;SCHEMBL3456107;DTXSID90546068;MFCD02714747;AKOS027393694;CS-0365500;1,3-Diphenylpyrazole-4-propionic acid, 97%;3-(1,3-Diphenyl-1H-pyrazol-4-yl)propanoicacid;J-002143

Suppliers and Price of 1,3-Diphenylpyrazole-4-propionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(1,3-Diphenyl-1H-pyrazol-4-yl)propanoicAcid
100mg
$ 60.00

TRC
3-(1,3-Diphenyl-1H-pyrazol-4-yl)propanoicAcid
50mg
$ 45.00

Sigma-Aldrich
1,3-Diphenylpyrazole-4-propionic acid 97%
5g
$ 406.00

Sigma-Aldrich
1,3-Diphenylpyrazole-4-propionic acid 97%
1g
$ 98.60

Crysdot
3-(1,3-Diphenyl-1H-pyrazol-4-yl)propanoicacid 97%
5g
$ 452.00

Biosynth Carbosynth
1,3-Diphenylpyrazole-4-propionic acid
5 g
$ 442.80

Biosynth Carbosynth
1,3-Diphenylpyrazole-4-propionic acid
10 g
$ 708.40

Biosynth Carbosynth
1,3-Diphenylpyrazole-4-propionic acid
500 mg
$ 60.00

Biosynth Carbosynth
1,3-Diphenylpyrazole-4-propionic acid
2 g
$ 276.80

Biosynth Carbosynth
1,3-Diphenylpyrazole-4-propionic acid
1 g
$ 148.70

Total 8 raw suppliers

Chemical Property of 1,3-Diphenylpyrazole-4-propionic acid

Chemical Property:

Vapor Pressure:2.92E-11mmHg at 25°C
Melting Point:140-144 °C
Refractive Index:1.618
Boiling Point:510.9°C at 760 mmHg
Flash Point:262.8°C
PSA：55.12000
Density:1.18g/cm³
LogP:3.55650
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:292.121177757
Heavy Atom Count:22
Complexity:362

Purity/Quality:

97% ^*data from raw suppliers

3-(1,3-Diphenyl-1H-pyrazol-4-yl)propanoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NN(C=C2CCC(=O)O)C3=CC=CC=C3

Technology Process of 1,3-Diphenylpyrazole-4-propionic acid

There total 9 articles about 1,3-Diphenylpyrazole-4-propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.2%

: 73221-47-3,519137-38-3
(E)-3-(1,3-Diphenyl-1H-pyrazol-4-yl)-acrylic acid

: 108446-77-1
3-(1,3-diphenyl-1H-pyrazol-4-yl)propanoic acid

Guidance literature:: With hydrogen; platinum(IV) oxide; In tetrahydrofuran; for 7h; Ambient temperature;

Reference yield: 76.0%

: 2033-24-1
cycl-isopropylidene malonate

: 21487-45-6
1,3-diphenyl-4-formylpyrazole

: 108446-77-1
3-(1,3-diphenyl-1H-pyrazol-4-yl)propanoic acid

Guidance literature:: With triethylamine-formic acid; at 95 - 100 ℃; for 2h;

Reference yield:

: 21487-45-6
1,3-diphenyl-4-formylpyrazole

: 108446-77-1
3-(1,3-diphenyl-1H-pyrazol-4-yl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / pyridine; piperidine / 4 h / Heating

2: 64 percent / NaOH; hydrazine hydrate / Renay nickel / ethanol / Heating

With piperidine; pyridine; sodium hydroxide; hydrazine hydrate; Renay nickel; In ethanol;
DOI:10.1023/A:1020905727368