1H-Benzimidazole,1-(2-methyl-2-propenyl)-(9CI)

Base Information

• Chemical Name: 1H-Benzimidazole,1-(2-methyl-2-propenyl)-(9CI)
• CAS No.: 108413-23-6
• Molecular Formula: C11H12 N2
• Molecular Weight: 172.23
• Hs Code.: 2933990090
• Mol file: 108413-23-6.mol

Synonyms:1H-Benzimidazole,1-(2-methyl-2-propenyl)- (9CI)

Chemical Property of 1H-Benzimidazole,1-(2-methyl-2-propenyl)-(9CI)

Chemical Property:

• PSA: 17.82000
• LogP: 2.61240

Purity/Quality:

1-(2-METHYL-2-PROPENYL)-1H-BENZIMIDAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Benzimidazole,1-(2-methyl-2-propenyl)-(9CI)

There total 6 articles about 1H-Benzimidazole,1-(2-methyl-2-propenyl)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

benzoimidazole (51-17-2,79351-71-6) + 2-methyl-3-bromo-1-propene (1458-98-6) → 1‐(2‐methylallyl)benzimidazole (108413-23-6)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; Cooling; Schlenk technique;

DOI:10.1002/ejoc.201301243

Reference yield: 91.0%

benzoimidazole (51-17-2,79351-71-6) + 3-Chloro-2-methylpropene (563-47-3) → 1‐(2‐methylallyl)benzimidazole (108413-23-6)

Guidance literature:

benzoimidazole; With potassium hydroxide; In dimethyl sulfoxide; for 0.75h; Inert atmosphere; Schlenk technique;

3-Chloro-2-methylpropene; In dimethyl sulfoxide; for 3.5h; Inert atmosphere; Schlenk technique; Cooling with ice;

DOI:10.1002/ejoc.201301243

Reference yield: 78.0%

benzoimidazole (51-17-2,79351-71-6) → 1‐(2‐methylallyl)benzimidazole (108413-23-6)

Guidance literature:

benzoimidazole; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere; Schlenk technique;

(2-methylallyl) halide; In tetrahydrofuran; at 60 ℃; for 24h; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.jorganchem.2020.121285

upstream raw materials:

benzoimidazole

2-methyl-3-bromo-1-propene

3-Chloro-2-methylpropene

1-allylbenzimidazole

Downstream raw materials:

2,3-dihydro-2-methyl-1H-pyrrolo[1,2-a]benzimidazole