aspidospermidine

Base Information

• Chemical Name: aspidospermidine
• CAS No.: 7689-02-3
• Molecular Formula: C₁₉H₂₆N₂
• Molecular Weight: 282.429
• Mol file: 7689-02-3.mol

Synonyms:aspidospermidine

Chemical Property of aspidospermidine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of aspidospermidine

There total 126 articles about aspidospermidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C26H26N2 → (+)-aspidospermidine (7013-58-3,7689-02-3,32975-45-4,52152-79-1,2912-09-6)

Guidance literature:

With hydrogen; palladium(II) hydroxide; In methanol; ethyl acetate; at 23 ℃; under 10343.2 Torr;

DOI:10.1038/nature10232

Reference yield: 90.0%

5-oxo-aspidospermidine (477904-34-0) → (+)-aspidospermidine (7013-58-3,7689-02-3,32975-45-4,52152-79-1,2912-09-6)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 3h; Heating;

DOI:10.1021/ja026357f

Reference yield: 83.0%

(+)-1,2-didehydroaspidospermidine (19751-76-9,56245-51-3,65377-84-6) → (+)-aspidospermidine (7013-58-3,7689-02-3,32975-45-4,52152-79-1,2912-09-6)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at -78 ℃; for 12h; Reflux;

DOI:10.1021/acs.orglett.7b01292

upstream raw materials:

(+)-2,3-Didehydro-1-<(4-methoxyphenyl)sulfonyl>aspidospermidin-10-one

(3¹S,6aR,9aR)-6a-ethyloctahydro-1H-pyrrolo[3,2,1-ij]quinolin-9(2H)-one

phenylhydrazine

5-oxo-aspidospermidine

Downstream raw materials:

(+)-vincadifformine

(+)-1,2-didehydroaspidospermidine

(-)-N-acetylaspidospermidine

(-)-demethoxypalosine