amino[2-chloro-4-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl] phenyl] acetonitrile

Base Information

Chemical Name:amino[2-chloro-4-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl] phenyl] acetonitrile
CAS No.:950482-51-6
Molecular Formula:C₁₈H₁₁Cl₃F₃N₃O
Molecular Weight:448.659
Hs Code.:

Synonyms:amino[2-chloro-4-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl] phenyl] acetonitrile

Suppliers and Price of amino[2-chloro-4-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl] phenyl] acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of amino[2-chloro-4-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl] phenyl] acetonitrile

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of amino[2-chloro-4-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl] phenyl] acetonitrile

There total 9 articles about amino[2-chloro-4-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl] phenyl] acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67492-50-6
(3,5-dichlorophenyl)boronic acid

: 950482-51-6
amino[2-chloro-4-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl] phenyl] acetonitrile

Guidance literature:: Multi-step reaction with 7 steps

1.1: potassium carbonate / bis-triphenylphosphine-palladium(II) chloride / tetrahydrofuran; water / 3 h / Heating / reflux

2.1: N-chloro-succinimide / 1,2-dimethoxyethane / 2 h / 70 °C

2.2: 20 h / 20 °C

3.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / 1,2-dichloro-ethane / 3 h / 70 °C

4.1: acetic acid / 2 h / 120 °C

4.2: 20 °C

5.1: sodium hydroxide; ethanol; water / 1 h / 100 °C

6.1: pyridinium chlorochromate / dichloromethane / 20 h / 20 °C

7.1: ammonia; ammonium chloride / methanol; water / 2 h / 60 °C

With sodium hydroxide; N-chloro-succinimide; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); ethanol; ammonia; water; potassium carbonate; ammonium chloride; acetic acid; pyridinium chlorochromate; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; dichloromethane; water; 1,2-dichloro-ethane;

Reference yield:

: 930110-27-3
2-chloro-4-[5-(3,5-dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-benzaldehyde

: 143-33-9,25596-52-5
sodium cyanide

: 950482-51-6
amino[2-chloro-4-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl] phenyl] acetonitrile

Guidance literature:: With ammonia; ammonium chloride; In methanol; water; at 60 ℃; for 2h;

Reference yield:

: 930110-22-8
3-[3-chloro-4-(hydroxymethyl)phenyl]-5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazole

: 950482-51-6
amino[2-chloro-4-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl] phenyl] acetonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: pyridinium chlorochromate / dichloromethane / 20 h / 20 °C

2: ammonia; ammonium chloride / methanol; water / 2 h / 60 °C

With ammonia; ammonium chloride; pyridinium chlorochromate; In methanol; dichloromethane; water;