3-methoxy-4-fluorobenzyl-bis(tert-butoxycarbonyl)-guanidine

Base Information

• Chemical Name: 3-methoxy-4-fluorobenzyl-bis(tert-butoxycarbonyl)-guanidine
• CAS No.: 1037078-82-2
• Molecular Formula: C₁₉H₂₈FN₃O₅
• Molecular Weight: 397.447
• Mol file: 1037078-82-2.mol

Synonyms:3-methoxy-4-fluorobenzyl-bis(tert-butoxycarbonyl)-guanidine

Chemical Property of 3-methoxy-4-fluorobenzyl-bis(tert-butoxycarbonyl)-guanidine

Chemical Property:

Purity/Quality:

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Technology Process of 3-methoxy-4-fluorobenzyl-bis(tert-butoxycarbonyl)-guanidine

There total 1 articles about 3-methoxy-4-fluorobenzyl-bis(tert-butoxycarbonyl)-guanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

(4-fluoro-3-methoxyphenyl)methanamine (508177-67-1) + (Z)-tert-butyl (((tert-butoxycarbonyl)imino)(1H-pyrazol-1-yl)methyl)carbamate (152120-54-2,862686-58-6,1143572-00-2) → 3-methoxy-4-fluorobenzyl-bis(tert-butoxycarbonyl)-guanidine (1037078-82-2)

Guidance literature:

In acetonitrile; for 0.5h;

Reference yield: 100.0%

3-methoxy-4-fluorobenzyl-bis(tert-butoxycarbonyl)-guanidine (1037078-82-2) → 3-methoxy-4-fluorobenzylguanidinium chloride (1037078-53-7)

Guidance literature:

With hydrogenchloride; water; In 1,4-dioxane; at 20 ℃; for 24h;

upstream raw materials:

(4-fluoro-3-methoxyphenyl)methanamine

(Z)-tert-butyl (((tert-butoxycarbonyl)imino)(1H-pyrazol-1-yl)methyl)carbamate

Downstream raw materials:

3-methoxy-4-fluorobenzylguanidinium chloride