β-phenylethyl trichloroacetimidate

Base Information

• Chemical Name: β-phenylethyl trichloroacetimidate
• CAS No.: 99421-73-5
• Molecular Formula: C₁₀H₁₀Cl₃NO
• Molecular Weight: 266.554
• Mol file: 99421-73-5.mol

Synonyms:β-phenylethyl trichloroacetimidate

Chemical Property of β-phenylethyl trichloroacetimidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of β-phenylethyl trichloroacetimidate

There total 1 articles about β-phenylethyl trichloroacetimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-phenylethanol (60-12-8) + trichloroacetonitrile (545-06-2) → β-phenylethyl trichloroacetimidate (99421-73-5)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane;

DOI:10.1021/jacs.7b05214

Reference yield: 99.0%

β-phenylethyl trichloroacetimidate (99421-73-5) → 4-phenyl-2-(trichloromethyl)-4,5-dihydrooxazole

Guidance literature:

With iodine; (2-(N-methylbenzamido)phenyl)-l 3-iodanediyl diacetate; potassium carbonate; In dichloromethane; at 20 ℃; for 3h; Irradiation;

DOI:10.1002/adsc.202100316

Reference yield: 91.0%

β-phenylethyl trichloroacetimidate (99421-73-5) → Phenylglycinol (20989-17-7,56613-80-0,71006-16-1,7568-92-5,188586-38-1)

Guidance literature:

β-phenylethyl trichloroacetimidate; With phthaloyl peroxide; cesium iodide; In acetonitrile; at 20 ℃; for 2h; Irradiation; Inert atmosphere;

With hydrogenchloride; In methanol; water; acetonitrile; for 2h; Reagent/catalyst; Inert atmosphere;

DOI:10.1002/anie.202008806

upstream raw materials:

2-phenylethanol

trichloroacetonitrile

Downstream raw materials:

trichloro-acetic acid phenethylamide

Phenylglycinol

4-phenyl-2-oxazolidinone

N-α-phenylethylacetamide