7-{[Amino(phenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Base Information

Chemical Name:7-{[Amino(phenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS No.:108260-04-4
Molecular Formula:C16H17 N3 O4 S
Molecular Weight:347.395
Hs Code.:
DSSTox Substance ID:DTXSID20274382,DTXSID80860169
ChEMBL ID:CHEMBL287590
Mol file:108260-04-4.mol

Synonyms:L-Cephalexin;108260-04-4;34632-04-7;7-{[amino(phenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;Cephalexin hydrate;(6R,7R)-7-[(R)-2-Amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]-oct-2-ene-2-carboxylic acid monohydrate;7-[(2-amino-2-phenylacetyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;CHEMBL287590;SCHEMBL10713860;DTXSID20274382;DTXSID80860169;HMS3393A04;BBL013211;STK803646;AKOS005611612;NCGC00015241-02;NCGC00015241-03;NCGC00094945-01;NCGC00094945-02;7-(D-.alpha.-Amino-.alpha.-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid monohydrate;FT-0603008;FT-0664460;[6R-[6.alpha.,7.beta.(R*)]]-7-[(Aminophenylacetyl)amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(aminophenylacetyl)amino]-3-methyl-8-oxo-, monohydrate [6R-[6.alpha.,7.beta.(R*)]]-;7-([Amino(phenyl)acetyl]amino)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid #;7-(2-Amino-2-phenylacetamido)-3-methyl-8-oxo-5- thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;7-(aminophenylacetyl)amino-3-methyl-8-oxo-5-thia-1-azabicyclo(4,2,0)oct-2-ene-2-carboxylic acid;7-[2-Amino(phenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Suppliers and Price of 7-{[Amino(phenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 7-{[Amino(phenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Chemical Property:

PSA：141.52000
LogP:1.92340
XLogP3:0.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:347.09397721
Heavy Atom Count:24
Complexity:600

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N2C(C(C2=O)NC(=O)C(C3=CC=CC=C3)N)SC1)C(=O)O

Technology Process of 7-{[Amino(phenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

There total 35 articles about 7-{[Amino(phenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.7%

: 7-ADCA

: 25705-52-6
(R)-phenylglycine hydrochloride

: 15686-71-2,27726-35-8,34632-04-7,79814-91-8,108260-04-4
cefalexin

Guidance literature:: 7-ADCA; With chloro-trimethyl-silane; triethylamine; In dichloromethane; at 20 ℃; for 1h;

(R)-phenylglycine hydrochloride; With N-trifluoroacetoxy succinimide; triethylamine; In dichloromethane; at -5 - 15 ℃; for 3h;

In dichloromethane; water; at 20 ℃; for 1h; pH=2; Reagent/catalyst; pH-value;