1-benzyl-3,4-dimethoxy-1H-pyrrole-2,5-dicarboxylic acid monomethyl ester

Base Information

Chemical Name:1-benzyl-3,4-dimethoxy-1H-pyrrole-2,5-dicarboxylic acid monomethyl ester
CAS No.:235434-21-6
Molecular Formula:C₁₆H₁₇NO₆
Molecular Weight:319.314
Hs Code.:

1-benzyl-3,4-dimethoxy-1<i>H</i>-pyrrole-2,5-dicarboxylic acid monomethyl ester

Synonyms:1-benzyl-3,4-dimethoxy-1H-pyrrole-2,5-dicarboxylic acid monomethyl ester

Suppliers and Price of 1-benzyl-3,4-dimethoxy-1H-pyrrole-2,5-dicarboxylic acid monomethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-benzyl-3,4-dimethoxy-1H-pyrrole-2,5-dicarboxylic acid monomethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-benzyl-3,4-dimethoxy-1H-pyrrole-2,5-dicarboxylic acid monomethyl ester

There total 1 articles about 1-benzyl-3,4-dimethoxy-1H-pyrrole-2,5-dicarboxylic acid monomethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 148528-46-5
dimethyl 1-benzyl-3,4-dimethoxypyrrole-2,5-dicarboxylate

: 235434-21-6
1-benzyl-3,4-dimethoxy-1H-pyrrole-2,5-dicarboxylic acid monomethyl ester

Guidance literature:: With potassium tert-butylate; water; In tetrahydrofuran; at 0 ℃; for 12h;
DOI:10.1002/(SICI)1521-3773(19990517)38:10<1442::AID-ANIE1442>3.0.CO;2-R

Reference yield: 86.0%

: 235434-21-6
1-benzyl-3,4-dimethoxy-1H-pyrrole-2,5-dicarboxylic acid monomethyl ester

: 235434-22-7
1-benzyl-5-iodo-3,4-dimethoxy-1H-pyrrole-2-carboxylic acid methyl ester

Guidance literature:: With iodine; sodium carbonate; potassium iodide; at 20 ℃; for 12h;
DOI:10.1002/(SICI)1521-3773(19990517)38:10<1442::AID-ANIE1442>3.0.CO;2-R

Reference yield:

: 235434-21-6
1-benzyl-3,4-dimethoxy-1H-pyrrole-2,5-dicarboxylic acid monomethyl ester

: 235434-25-0
1-benzyl-2-iodo-3,4-dimethoxy-5-phenyl-1H-pyrrole

Guidance literature:: Multi-step reaction with 4 steps

1: 86 percent / I₂; KI; Na₂CO₃ / 12 h / 20 °C

2: 71 percent / Pd[PPh₃]4 / 1,2-dimethoxy-ethane

3: 76 percent / tert-BuOK; H₂O / tetrahydrofuran / 12 h / 0 °C

4: 82 percent / I₂; KI; Na₂CO₃ / 12 h / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium tert-butylate; water; iodine; sodium carbonate; potassium iodide; In tetrahydrofuran; 1,2-dimethoxyethane; 1: Decarboxylation / 2: Phenylation / 3: Hydrolysis / 4: Decarboxylation;
DOI:10.1002/(SICI)1521-3773(19990517)38:10<1442::AID-ANIE1442>3.0.CO;2-R